Anatomic and Visual Outcomes of Non-Infectious Endophthalmitis After Intravitreal Triamcinolone

Abstract

 

Purpose:

 

To describe the anatomic and visual outcomes of patients whodeveloped non-infectious endophthalmitis following injectionof intravitreal triamcinolone acetonide.

 

Methods:

 

A noncomparative retrospective case series was conducted inseventeen eyes of seventeen patients that developed non-infectiousendophthalmitis following intravitreal triamcinolone. Evaluationsof patients used Snellen visual acuity and mean foveal thicknessby ocular coherence tomography. Evaluations took place on theday of injection, presentation of non-infectious endophthalmitis,time of clearance of inflammation, and on follow-up exam.

 

Results:

 

Mean visual acuity and mean foveal thickness on the day of injectionof intravitreal triamcinolone were 20/132 (logMAR 0.8206) and432µm respectively. Mean visual acuity at time of non-infectiousendophthalmitis (mean=1.9 days) was 20/4444 (logMAR 2.3508).At follow-up (mean=57.6 days) visual acuity and mean fovealthickness was 20/56 (logMAR 0.4435) and 301µm respectively.

 

Conclusions:

 

Visual acuity and mean foveal thickness in all patients withnon-infectious endophthalmitis after intravitreal triamcinoloneimproved to better than pre-injection levels in this series.No patient suffered long term visual loss from non-infectiousendophthalmitis. Non-infectious endophthalmitis after intravitrealtriamcinolone may not exclude good visual and anatomic prognoses.  

 

 

Keywords: endophthalmitis • corticosteroids • edema