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M. Basile, A. Ostrovsky, J. Danias, R. Rothman, A. Prywes, C. Marcus, J. B. Serle; Effect of Third and Fourth SLT on IOP. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1241.
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© ARVO (1962-2015); The Authors (2016-present)
To assess efficacy of third and fourth Selective Laser Trabeculoplasty (SLT) in patients with increased IOP.
Charts of 20 patients (n=20 eyes) that received at least 3 SLTs between April 2002 and November 2007 were retrospectively reviewed. Patients were predominantly white (90%), diagnosed with OAG (30%), PXG (45%), CAG (10%), mixed mechanism glaucoma (5%) and pigmentary glaucoma (5%). 7 eyes (35%) underwent a fourth SLT. All 7 patients were Caucasian and diagnosed with OAG (57%) or PXG (43%). IOP was recorded at baseline (<4 weeks pre-SLT), and post-SLT at <1 month, 1,3,6,9,12,15 months. Number of medications at each time point was recorded. Failure of treatment was defined as the need for additional SLT or surgical intervention. Comparison of IOP values and number of medications at the various time points was performed by ANOVA. Kaplan-Meier survival curves were generated.
Mean age of patients undergoing 3rd SLT was 73+13 years. Baseline IOP prior to 3rd SLT was 23+6.6 mmHg. Mean number of medications at baseline were 3.3+1.5. All post-operative IOPs and number of medications for eyes not considered failures, were not different (p>0.05) from baseline for both 3rd and 4th SLTs. Survival analysis determined ~30% of 3rd SLTs failed by 3 months and ~50% by 6 months. Mean age of patients undergoing a 4th SLT was 67+11yrs. Baseline IOP prior to 4th SLT was 22.9+6 mmHg. Mean number of medications at baseline was 2.9+1.1. Survival analysis revealed 60% of 4th SLTs failed by 1 month and 75% failed by 5 months.
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