May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Is It Worth to Remove the Lens During Vitrectomy for Stage 4b and 5 ROP?
Author Affiliations & Notes
  • C. Angora
    Ophthalmology, Catholic University, Rome, Italy
  • L. Orazi
    Ophthalmology, Catholic University, Rome, Italy
  • D. Lepore
    Ophthalmology, Catholic University, Rome, Italy
  • F. Molle
    Ophthalmology, Catholic University, Rome, Italy
  • M. M. Pagliara
    Ophthalmology, Catholic University, Rome, Italy
  • G. D'Amico
    Ophthalmology, Catholic University, Rome, Italy
  • A. Baldascino
    Ophthalmology, Catholic University, Rome, Italy
  • M. Laguardia
    Ophthalmology, Catholic University, Rome, Italy
  • F. Lafranceschina
    Ophthalmology, Catholic University, Rome, Italy
  • E. Balestrazzi
    Ophthalmology, Catholic University, Rome, Italy
  • Footnotes
    Commercial Relationships  C. Angora, None; L. Orazi, None; D. Lepore, None; F. Molle, None; M.M. Pagliara, None; G. D'Amico, None; A. Baldascino, None; M. Laguardia, None; F. Lafranceschina, None; E. Balestrazzi, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1391. doi:
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      C. Angora, L. Orazi, D. Lepore, F. Molle, M. M. Pagliara, G. D'Amico, A. Baldascino, M. Laguardia, F. Lafranceschina, E. Balestrazzi; Is It Worth to Remove the Lens During Vitrectomy for Stage 4b and 5 ROP?. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1391.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : to evaluate the usefulness of lens removal in vitrectomy for stage 4 and 5 ROP.

Methods: : from August 2004 to November 2007 , 42 eyes of 24 pre-term babies (9 of them outborn) underwent vitrectomy for stage 4b and 5 ROP. Lens sparing vitrectomy (LSV) was performed in 20 eyes (11 babies) at mean postcoceptional age (PCA) of 45.9 weeks . In 22 eyes (14 babies) we performed vitrectomy and lensectomy at the same time. Structural result after a mean follow up of 10 months (ranging from 3 months to 28 months) were evaluated.

Results: : cataract is a common late complication of retinal surgery. In our experience all LSV-treated babies developed some degree of lens opacities within 12 to 24 months after surgery. 10 eyes from 7 babies required late lensectomy. The mean time of cataract removal was 96.9wks PCA . A 59% of favourable outcomes ( as defined by Cryo-ROP study) was found in babies underwent lensectomy and vitrectomy at the same time against a 25% of favourable outcomes in LSV.

Conclusions: : lens removal allows a wide and more complete peeling of preretinal fibrosis in stage 4b and 5 ROP. On the other hand LSV save the normal anatomy of the eyes and reduces postoperative recovery -time together with the risk of synechiae. In our experience LSV advantages are overwhelming with better retinal results we have been able to achieve with vitrectomy with lens removal.

Keywords: retinopathy of prematurity • vitreoretinal surgery • cataract 
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