May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Accuracy of Retinopathy of Prematurity Diagnosis by Retinal Fellows Compared to Experts
Author Affiliations & Notes
  • R. V. Chan
    Ophthalmology, Weill Med College Cornell Univ, New York, New York
  • S. L. Williams
    Ophthalmology, Columbia University College of Physicians and Surgeons, New York, New York
  • Y. Yonekawa
    Ophthalmology, Weill Med College Cornell Univ, New York, New York
  • L. Wang
    Ophthalmology, Columbia University College of Physicians and Surgeons, New York, New York
  • T. C. Lee
    Ophthalmology, Childen's Hospital Los Angeles, New York, New York
  • M. F. Chiang
    Ophthalmology, Columbia University College of Physicians and Surgeons, New York, New York
  • Footnotes
    Commercial Relationships  R.V. Chan, None; S.L. Williams, None; Y. Yonekawa, None; L. Wang, None; T.C. Lee, None; M.F. Chiang, Unpaid member of Scientific Advisory Board at Clarity Medical Systems (Pleasanton, CA), C.
  • Footnotes
    Support  NIH Grant EY13972 (MFC), Research to Prevent Blindness Career Development Award (MFC), St. Giles Foundation (RVPC), Starr Foundation (SLW), Doris Duke Foundation (SLW)
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1402. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      R. V. Chan, S. L. Williams, Y. Yonekawa, L. Wang, T. C. Lee, M. F. Chiang; Accuracy of Retinopathy of Prematurity Diagnosis by Retinal Fellows Compared to Experts. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1402. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : To measure the accuracy of retinopathy of prematurity (ROP) diagnosis by retinal fellows compared to that of an expert pediatric retinal specialist.

Methods: : An atlas of 804 retinal images was captured from 248 eyes of 67 premature infants with a wide-angle camera (RetCam-II; Clarity Medical Systems, Pleasanton, CA). Images were uploaded to a study website, from which an expert pediatric retinal specialist and seven retinal fellows independently reviewed and provided a diagnosis (no ROP, mild ROP, type-2 ROP, or treatment-requiring ROP) for each eye. Sensitivity and specificity of each retinal fellow was calculated, compared to a reference standard of diagnosis by the expert specialist. Images were divided into those captured at 31-33 weeks post menstrual age (PMA) and those captured at 35-37 weeks PMA.

Results: : Six fellows had no ROP screening experience, and one fellow had a year of experience. For fellows at 31-33 weeks PMA: (a) sensitivity and specificity of fellows for identifying mild or worse ROP ranged from 0.684-0.921 (mean 0.813) and 0.700-0.965 (mean 0.835) respectively; and (b) sensitivity and specificity for identifying type-2 or worse ROP ranged from 0.000-0.889 (mean 0.569) and 0.780- 0.990 (mean 0.927) respectively. For fellows at 35-37 weeks PMA: (a) sensitivity and specificity for identifying mild ROP or worse were 0.909-1.000 (mean 0.967) and 0.774-0.980 (mean 0.887) respectively; (b) sensitivity and specificity for identifying type 2 or worse ROP were 0.576-1.000 (mean 0.809) and 0.655- 0.976 (mean 0.856) respectively; and (c) sensitivity and specificity for identifying treatment-requiring ROP were 0.769-1.000 (mean 0.947) and 0.745-0.971 (mean 0.874) respectively.

Conclusions: : Performance of fellows for ROP diagnosis was less than that of the expert grader, particularly for detection of clinically-significant disease. This raises potential concerns about the quality of ROP screening performed by inexperienced examiners, and may indicate that formal training in ROP screening is required to provide appropriate care for this devastating condition.

Keywords: retinopathy of prematurity • imaging/image analysis: clinical • retina 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×