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J. A. Urrets-Zavalia, F. Espósito, E. G. Knoll, E. Collino, H. M. Serra, E. A. Urrets-Zavalía; Retinopathy of Prematurity (rop) in Unusual Premature Infants. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1444.
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© ARVO (1962-2015); The Authors (2016-present)
To study de prevalence of ROP in unusual premature infants (UPI), severity of ROP, need for treatment and differences between UPI and premature infants (PI) of BW ≤1500 g and or GA ≤32 weeks, born at or with a referral ≤24 h to a 3rd level attention public hospital of Córdoba, Argentina.Materials and
Premature infants with BW ≤1500 g and/or GA ≤32 weeks, and those UPI > 1500 g and/or > 32-36 weeks with clinical unstable evolution or risk factor for ROP were evaluated retrospectively in the Neonatology department of a 3rd level attention public hospital in Córdoba, Argentina , between january 2003 december 2006. Both eyes of all infants were fully dilated and examined with a binocular indirect ophthalmoscope and a +20 d lens by 2 experienced ophthalmologist in ROP. First exam was performed between the 3rd and the 6th week. ROP prevalence, distribution of stage, and need for treatment was evaluated among PI and UPI.
Of the 1532 evaluated infants, 1038 (67.75%) were born with >1500 g, and 494 (32.24%) ≤1500 g; 1050 (68.53%) had a GA of >32 weeks and 482 (31.46%) had ≤32 weeks. ROP was detected in 344/1532 (22.45%) of infants; 54 (15.69 %) of whom received laser treatment. 252/494 (51%) PI of ≤1500 gr and 92/1038 (8.86%) UPI of >1500 g (p=<0.001), and 242/482 (50.21%) PI of GA ≤32 weeks and 102/1050 (9.71%) of UPI (p=<0.001) developed ROP. 18.25% PI of ≤1500 g and 8.63% UPI of >1500 g (p=0.043), and 19.00% of GA ≤32 weeks and 7.84% of GA >32 weeks (p=0.009) needed treatment.
The prevalence of UPI was high, compared with other studies. The global prevalence of ROP in our study was 22.45%. Although lower than in PI, severe ROP was not infrequent among UPI.
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