May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Incidence of Endophthalmitis Following Intravitreal Injection Among the U.S. Medicare Population
Author Affiliations & Notes
  • G. H. Davis
    Ophthalmology, Univ of Texas Medical Branch, Galveston, Texas
  • D. Zhang
    Ophthalmology, Univ of Texas Medical Branch, Galveston, Texas
  • J. Freeman
    Ophthalmology, Univ of Texas Medical Branch, Galveston, Texas
  • Footnotes
    Commercial Relationships  G.H. Davis, None; D. Zhang, None; J. Freeman, None.
  • Footnotes
    Support  R24HS011618
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1759. doi:https://doi.org/
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    • Get Citation

      G. H. Davis, D. Zhang, J. Freeman; Incidence of Endophthalmitis Following Intravitreal Injection Among the U.S. Medicare Population. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1759. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To Estimate the annual incidence of presumed endophthalmitis associated with intravitreal injections

Methods: : Medicare 5% sample beneficiary data files for outpatient visits from 2000 to 2005 were analyzed to identify all intravitreal injections and subsequent cases of endophthalmitis after injection.

Results: : The number of intravitreal injections identified using our protocol increased from 101 to 4,298 over the five year period. Incidence of endophthalmitis was 2% in 2000 compared to 0.5% in 2005.

Conclusions: : The risk of endophthalmitis following intravitreal injection has decreased over the past 5 years. Given the benefit of recent intravitreal injections, the risk of infection is sufficiently low to justify a reasonable risk to benefit ratio.

Keywords: injection • endophthalmitis 
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