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G. H. Davis, D. Zhang, J. Freeman; Incidence of Endophthalmitis Following Intravitreal Injection Among the U.S. Medicare Population. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1759.
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© ARVO (1962-2015); The Authors (2016-present)
To Estimate the annual incidence of presumed endophthalmitis associated with intravitreal injections
Medicare 5% sample beneficiary data files for outpatient visits from 2000 to 2005 were analyzed to identify all intravitreal injections and subsequent cases of endophthalmitis after injection.
The number of intravitreal injections identified using our protocol increased from 101 to 4,298 over the five year period. Incidence of endophthalmitis was 2% in 2000 compared to 0.5% in 2005.
The risk of endophthalmitis following intravitreal injection has decreased over the past 5 years. Given the benefit of recent intravitreal injections, the risk of infection is sufficiently low to justify a reasonable risk to benefit ratio.
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