May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Development of a Wireless Neural Record System
Author Affiliations & Notes
  • G. Swider
    Ctr for Innovative Visual Rehabilitation, Boston VA Med Ctr, Boston, Massachusetts
    Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts
  • W. Drohan
    Ctr for Innovative Visual Rehabilitation, Boston VA Med Ctr, Boston, Massachusetts
    Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts
  • S. J. Kim
    Ctr for Innovative Visual Rehabilitation, Boston VA Med Ctr, Boston, Massachusetts
    Dep. of Ophthalmology, Massachusetts Eye & Ear Infirmary, Boston, Massachusetts
  • J. F. Rizzo
    Ctr for Innovative Visual Rehabilitation, Boston VA Med Ctr, Boston, Massachusetts
    Dep. of Ophthalmology, Massachusetts Eye & Ear Infirmary, Boston, Massachusetts
  • S. K. Kelly
    Ctr for Innovative Visual Rehabilitation, Boston VA Med Ctr, Boston, Massachusetts
    Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts
  • J. L. Wyatt
    Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts
  • Footnotes
    Commercial Relationships  G. Swider, None; W. Drohan, None; S.J. Kim, None; J.F. Rizzo, None; S.K. Kelly, None; J.L. Wyatt, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1772. doi:https://doi.org/
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      G. Swider, W. Drohan, S. J. Kim, J. F. Rizzo, S. K. Kelly, J. L. Wyatt; Development of a Wireless Neural Record System. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1772. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : This work is related to the efforts of the Boston Retinal Implant Project to develop a sub-retinal prosthesis to restore vision to the blind. The specific purpose of this project was to develop a wireless recording system in order to gain greater insights about neurological response patterns. This system in capable of recording microvolt signals from the test subject and transmitting the signals over a wireless local area network to a nearby computer. The test subject is allowed free movements because of the small size and portability of the recording system.

Methods: : The system on the test subject is microcontroller based. The microcontroller interfaces with three peripheral devices: multiplexer for switching between neural record sites, an amplifier and a RF transmitter. The system on the test subject is battery powered. In order to conserve power, the microcontroller operates in a low power shutdown mode the majority of the time. It is capable of powering up in a periodic manner to perform recording and transmission. The carrier frequency for RF transmission is 2.4GHz.

Results: : As the system evolved it has been in fairly constant experimental use. The recordings have been shown to cover a wide range of possible stimulation patterns. The recording system has been shown to obtain reproducible response patterns.

Conclusions: : The system has worked effectively in recording biological signals but the experimental program needs to be continually expanded to include more complex stimulation and recording patterns.

Keywords: neuro-ophthalmology: diagnosis • electrophysiology: non-clinical 
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