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G. Swider, W. Drohan, S. J. Kim, J. F. Rizzo, S. K. Kelly, J. L. Wyatt; Development of a Wireless Neural Record System. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1772. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
This work is related to the efforts of the Boston Retinal Implant Project to develop a sub-retinal prosthesis to restore vision to the blind. The specific purpose of this project was to develop a wireless recording system in order to gain greater insights about neurological response patterns. This system in capable of recording microvolt signals from the test subject and transmitting the signals over a wireless local area network to a nearby computer. The test subject is allowed free movements because of the small size and portability of the recording system.
The system on the test subject is microcontroller based. The microcontroller interfaces with three peripheral devices: multiplexer for switching between neural record sites, an amplifier and a RF transmitter. The system on the test subject is battery powered. In order to conserve power, the microcontroller operates in a low power shutdown mode the majority of the time. It is capable of powering up in a periodic manner to perform recording and transmission. The carrier frequency for RF transmission is 2.4GHz.
As the system evolved it has been in fairly constant experimental use. The recordings have been shown to cover a wide range of possible stimulation patterns. The recording system has been shown to obtain reproducible response patterns.
The system has worked effectively in recording biological signals but the experimental program needs to be continually expanded to include more complex stimulation and recording patterns.
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