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M. Niessing, A. Messner, P.-W. Coenen, H. Röthgen, D. Hoehl, U. Thomas, EPIRET 3 group; The Epiret3 Wireless Intraocular Retina Implant System:Retina Prosthesis Production Techniques. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1782.
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development of a retina implant system as a retinal prothesis for RP patients.
a special external energy and signal transmission station for the retina implant system was constructed as to transmit energy to the implant (inductive) and signals via telemetry.The implant was encapsulated with silicone in order to achieve the biocompatibility properties which are required for a long-term implant. Due to the excellent biocompatibility the properties of the two-component silicone material which is used for the production of silicone intraocular lenses, the identical silicone quality was selected for the encapsulation of the implant, too.The encapsulation process was developed as a two-step moulding process using disposable polycarbonate moulds. With the first step a partial silicone layer is generated, the complete encapsulation of the implant is achieved with the second step.Next to the development of the stimulation software, TREC adopted their electrodes for the use with the implant. Prior to the application the implant was sterilized by ethylene oxide.
the system was successfully implanted and tested with several subjects.
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