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M. Ohji, M. Kakinoki, O. Sawada, T. Sawada, H. Kawamura; Comparison of Macular Thickness Between Cirrus HD OCT and Stratus OCT. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1853.
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To compare the macular thickness in normal subjects measured with Cirrus HD-Optical Coherence Tomography (OCT) (Carl Zeiss), spectral domain OCT, with macular thickness using Stratus OCT (Carl Zeiss), time domain OCT.
Macular thickness was measured using Cirrus HD-OCT and Status OCT in 30 eyes of 30 normal subjects with no eye diseases or diabetes mellitus and a best-corrected visual acuity of 20/20 or better. Macular thickness was measured by Fast Macula Thickness using Stratus OCT and by Macula Cube combo 200×200 using Cirrus HD-OCT.
The average macular thickness measured with Stratus OCT was 197.2 ± 18.6 µm and that measured with Cirrus HD-OCT was 258.2 ± 20.3 µm (p<0.01). The macular thickness measured with Stratus OCT correlated well with that measured with Cirrus HD-OCT (correlation coefficient, 0.915, p<0.01).
The macular measured with Cirrus HD-OCT is thicker than that measured with Stratus OCT and careful attention should be paid when comparing data measured using different OCT machines.
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