May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Multifocal-Electroretinographic and Oct Findings of Congenital Tilted Disc Syndrome
Author Affiliations & Notes
  • M. M. Moschos
    Ophthalmology, University of Athens, Athens, Greece
  • T. Rotsos
    Ophthalmology, University of Athens, Athens, Greece
  • C. Minogiannis
    Ophthalmology, University of Athens, Athens, Greece
  • S. Papadimitriou
    Ophthalmology, University of Athens, Athens, Greece
  • M. Apostolopoulos
    Ophthalmology, University of Athens, Athens, Greece
  • M. Moschos
    Ophthalmology, University of Athens, Athens, Greece
  • Footnotes
    Commercial Relationships  M.M. Moschos, None; T. Rotsos, None; C. Minogiannis, None; S. Papadimitriou, None; M. Apostolopoulos, None; M. Moschos, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1867. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      M. M. Moschos, T. Rotsos, C. Minogiannis, S. Papadimitriou, M. Apostolopoulos, M. Moschos; Multifocal-Electroretinographic and Oct Findings of Congenital Tilted Disc Syndrome. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1867. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : The purpose of this observational study is to report the findings of tilted disc syndrome by means of OCT and mf-ERG.

Methods: : Twenty three eyes of 14 patients with tilted disc syndrome (group A) were prospectively examined. Patients in group B (40 eyes of 21 patients) were age-matched control subjects. All patients underwent complete ophthalmological examination, including best-corrected visual acuity, tonometry, fundus examination, OCT and mf-ERG recording. Thickness of retinal nerve fiber layer along a 3.4-mm-diameter circle centered on the optic nerve head was evaluated using third-generation optical coherence tomography.

Results: : The mean foveal thickness measured by OCT in groups A and B was 237.3 µm (SD 43.62) and 169.47 µm (SD 10.167) respectively. The difference was considered extremely significant (P=0.0001). The mean retinal response density (RRD) in groups A and B was in area 1 was 10.4387 nV/deg² (SD 4.04) and 22.09 nV/deg² (SD 0.9) and the difference was considered extremely significant (P=0.0001). Group A had significantly thinner average nerve fiber layer in superior retinal area (P=0.004).

Conclusions: : Significant increase of retinal thickness of the macula and decrease of its electrical activity occurs in eyes with tilted disc syndrome. To the author’s knowledge, this is the first time a case series of tilted disc syndrome are documented by means of OCT and mf-ERG. These are the only tools in order to assess objectively the anatomical and functional damage accordingly.

Keywords: macula/fovea • electrophysiology: clinical • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×