May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Anterior Segment Biometry With Three-Dimensional Swept-Source Optical Coherence Tomography, Scheimpflug Camera, Scanning Slit Topography, and Ultrasound Pachymetry
Author Affiliations & Notes
  • M. Moriya
    Tsukuba Univ., Tsukuba city, Japan
    Ophthalmology,
    Computational Optics and Ophthalmology Group, Tsukuba, Japan
  • S. Fukuda
    Tsukuba Univ., Tsukuba city, Japan
    Ophthalmology,
    Computational Optics and Ophthalmology Group, Tsukuba, Japan
  • K. Kawana
    Tsukuba Univ., Tsukuba city, Japan
    Ophthalmology,
    Computational Optics and Ophthalmology Group, Tsukuba, Japan
  • Y. Yasuno
    Tsukuba Univ., Tsukuba city, Japan
    Computational Optics Group, Institute of Applied Physics,
    Computational Optics and Ophthalmology Group, Tsukuba, Japan
  • T. Oshika
    Tsukuba Univ., Tsukuba city, Japan
    Ophthalmology,
    Computational Optics and Ophthalmology Group, Tsukuba, Japan
  • Footnotes
    Commercial Relationships  M. Moriya, None; S. Fukuda, None; K. Kawana, None; Y. Yasuno, None; T. Oshika, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1870. doi:https://doi.org/
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      M. Moriya, S. Fukuda, K. Kawana, Y. Yasuno, T. Oshika; Anterior Segment Biometry With Three-Dimensional Swept-Source Optical Coherence Tomography, Scheimpflug Camera, Scanning Slit Topography, and Ultrasound Pachymetry. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1870. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate anterior segment biometry using three-dimensional swept-source optical coherence tomography, by comparing central corneal thickness (CCT) and anterior chamber depth (ACD) obtained with other devices.

Methods: : Forty eyes of 40 normal subjects (26 men and 14 women) were examined. The mean age of the subjects was 44.5 ± 20.7 (mean ± standard deviation; SD) years old. CCT and ACD were measured with 4 devices, i.e., three-dimensional cornea and anterior optical coherence tomography (3D CAS-OCT), Scheimpflug camera (SC), scanning slit topography (SST), and ultrasonic pachymetry (UP). Anterior chamber volume (ACV) was measured with 3D CAS-OCT.

Results: : A significant difference was observed in CCT measured with 4 devices (P < 0.0001, one way analysis of variance). The mean CCT was 547 ± 39.0, 590 ± 39.8, 525 ± 45.0, and 545 ± 20.7 µm with 3D CAS-OCT, SC, SST, and UP, respectively. The SC gave significantly higher CCT value than other devices (P < 0.001, Bonferroni multiple comparison). There were significant correlations between SS-OCT and SC (r = 0.639, P < 0.0001, Pearson’s correlation coefficient), SS-OCT and Orbscan (r = 0.908, P < 0.0001), and SS-OCT and USP (r = 0.977, P < 0.0001). ACD was 3.01 ± 0.47, 3.04 ± 0.52, and 2.88 ± 0.50 mm with 3D CAS-OCT, SC, SST, respectively. There were no significant differences in ACD among 3 methods (P = 0.678). In ACD measurements, there were significant correlations between 3D CAS-OCT and SC (r = 0.947, P < 0.0001), and 3D CAS-OCT and SST (r = 0.992, P < 0.0001). The mean ACV obtained with 3D CAS-OCT was 169.7 ± 23.1 mm3.

Conclusions: : The mean CCT was equivalent among 3D CAS-OCT, SST, and UP, but CCT obtained with SC was significantly larger than those with other devices. ACD obtained with SS-OCT, SC, and SST was comparable. The 3D CAS-OCT was a useful tool to noninvasively evaluate anterior segment biometry.

Clinical Trial: : www.umin.ac.jp/ctr/index/htm R000001087

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • cornea: clinical science • anterior chamber 
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