May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Three-Dimensional Vascular Structure Segmentation With Joint Spectral and Time Domain Optical Coherence Tomography
Author Affiliations & Notes
  • M. Szkulmowski
    Institute of Physics, Nicolaus Copernicus Univ, Torun, Poland
  • A. Szkulmowska
    Institute of Physics, Nicolaus Copernicus Univ, Torun, Poland
  • A. Kowalczyk
    Institute of Physics, Nicolaus Copernicus Univ, Torun, Poland
  • M. Wojtkowski
    Institute of Physics, Nicolaus Copernicus Univ, Torun, Poland
  • Footnotes
    Commercial Relationships  M. Szkulmowski, Optopol Technology SA, C; A. Szkulmowska, None; A. Kowalczyk, Optopol Technology SA, C; M. Wojtkowski, Optopol Technology SA, C.
  • Footnotes
    Support  Polish government scientific grants for years 2005-2008
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1874. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      M. Szkulmowski, A. Szkulmowska, A. Kowalczyk, M. Wojtkowski; Three-Dimensional Vascular Structure Segmentation With Joint Spectral and Time Domain Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1874. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : To demonstrate the capability of joint spectral and time domain optical coherence tomography to segment and visualize three-dimensional vascular structure of human eye in-vivo and to create velocity distribution maps of the retina. To demonstrate measurement protocols that allow for velocity distribution assessment with higher sensitivity then well established velocity estimation methods.

Methods: : The specialized measurement protocols and advanced filtering techniques has been developed and applied to data obtained from healthy volunteers. Novel methods of analysis and visualization of the segmented vascular structure has been introduced. All data presented in this contribution are obtained with the prototype high-resolution, high-speed Spectral OCT system constructed at the Nicolaus Copernicus University operating on an every-day basis at the ophthalmology clinic of the Collegium Medicum in Bydgoszcz, Poland.

Results: : In vivo high-speed, ultrahigh resolution OCT imaging has been performed in 10 eyes of 5 healthy volunteers. In all cases the three-dimensional vascular net is segmented in the macular region of the retina as well as in the proximity of the optic disk. We also present two-dimensional fundus-like maps indicating the direction and velocity value of blood flow. These en-face maps are correlated with fundus photography.

Conclusions: : Using three-dimensional joint spectral and time domain OCT and novel analysis tools we were able to segment volumes with blood flow. Due to the high sensitivity of the method, the blood flow not visible with other known velocity methods is also segmented. We believe that the novel technology can provide a better understanding of retinal functions. Our method enables significantly better visualization of three-dimensional vascular structure than was previously possible. It is also sensitive for small arteries and veins, which can be easily missed by other imaging technologies.

Keywords: retina • image processing 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×