May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Localized Cone-System Dysfunction and Normal Rod-System Function in Acute Zonal Occult Outer Retinopathy
Author Affiliations & Notes
  • K. Kuniyoshi
    Ophthalmology, Kinki University School of Medicine, Osaka-sayama, Japan
  • A. Nakao
    Ophthalmology, Kinki University School of Medicine, Osaka-sayama, Japan
  • C. Matsumoto
    Ophthalmology, Kinki University School of Medicine, Osaka-sayama, Japan
  • K. Ohmure
    Ophthalmology, Kinki University School of Medicine, Osaka-sayama, Japan
  • Y. Shimomura
    Ophthalmology, Kinki University School of Medicine, Osaka-sayama, Japan
  • Footnotes
    Commercial Relationships  K. Kuniyoshi, None; A. Nakao, None; C. Matsumoto, None; K. Ohmure, None; Y. Shimomura, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 2174. doi:https://doi.org/
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      K. Kuniyoshi, A. Nakao, C. Matsumoto, K. Ohmure, Y. Shimomura; Localized Cone-System Dysfunction and Normal Rod-System Function in Acute Zonal Occult Outer Retinopathy. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2174. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To report results of Goldmann perimetry (GP) recorded under scotopic, mesopic, and photopic condition in patients with acute zonal occult outer retinopathy (AZOOR).

 
Methods:
 

Patients were three males who were diagnosed as AZOOR. GP, full-field electroretinograms (ERGs), and multifocal ERGs were performed on all patients. Three types of background luminance were used in GP, namely, 0 cd/m2 (0 asb, scotopic GP), 10.0 cd/m2 (31.5 asb, mesopic GP), and 34 cd/m2 (106.8 asb, photopic GP). Scotopic GP was carried out after 15-minute dark adaptation, and photopic GP was performed after 10-minute light adaptation with a background light of 34 cd/m2.

 
Results:
 

All patients had a history of unilateral and sudden visual field abnormality, normal visual acuity, and unremarkable findings of funduscopy. Mesopic GP showed enlargement of the blind spot in all patients. The blind spot shown in photopic GP was much larger than that in mesopic GP, and the blind spot disappeared in scotopic GP in all cases. While the full-field ERG revealed reduced cone responses and normal rod responses, the multifocal ERG showed reduction of response density in the area of the blind spot.

 
Conclusions:
 

These results suggested localized cone-system dysfunction and normal rod-system function in patients with AZOOR.  

 
Keywords: retina • perimetry • photoreceptors 
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