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H. Kojima; Photoreceptor Integrity Determines Visual Acuity in Cystoid Macular Edema Associated With Retinitis Pigmentosa. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2178. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To assess the correlation between macular morphology and visual acuity in retinitis pigmentosa (RP) patients with cystoid macular edema (CME).
41 eyes of 28 RP patients with CME. They underwent cross section scan with optical coherence tomography. Age, total retinal thickness, photoreceptor thickness, transverse and vertical length of cystoid space were measured. Correlation between visual acuity and each measurement were examined. Additionally, the status of inner segment/outer segment junction (IS/OS) were determined as absent, discontinuous or distinct. Each measurement was compared among the three groups.
Total retinal thickness or photoreceptor thickness was not correlated with visual acuity. Transverse length of cystoid space was correlated with visual acuity thought the correlation coefficient was weak (r=0.28). Visual acuity in IS/OS absent group was worse than that in discontinuous or distinct IS/OS groups.
In monitoring CME associated with RP, the status of IS/OS was the most essential parameter.
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