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M. Watanabe, T. Sugawara, A. Hiramatsu, T. Ohira, K. Ogata, S. Yamamoto; Relationships Between Macular Function and the Nei Vfq-25 in Patients With Retinitis Pigmentosa. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2180.
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© ARVO (1962-2015); The Authors (2016-present)
To study the relationships between the vision-related quality of life and macular function in patients with retinitis pigmentosa (RP).
The Japanese version of the NEI VFQ-25 was used to study 30 patients with typical RP with visual acuity >0.8. The macular functions were evaluated by Humphrey field analyzer (HFA) 10-1 and fundus-related microperimetry (MP1). The mean deviation (MD) of HFA and the mean retinal sensitivity within central 10 degree determined with the MP1 were compared to the mean composite score in 10 sub-scales of the NEI VFQ-25.
The 10-subscale composite score in RP patient ranged from 39.4 to 86.0 (mean: 69.1). There was a significant correlation between the composite score and MD (r=0.63, P<0.05), and between the composite score and the retinal sensitivity (r=0.65, P<0.05).
The significant correlation between macular function and the vision-related QOL measured with the NEI VFQ-25 indicates that the NEI VFQ-25 can be used to measure visual functions subjectively in RP patients.
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