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S. Lupo, P. L. Grenga, S. Salvatore, R. Cannata, E. M. Vingolo; OCT Findings in RP Patients. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2190.
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to evalue the incidence of cystoid macular edema (CME), vitreoretinal traction and retinal thinning in RP patients.
our cohort of study comprehend 90 consecutive patients, 180 eyes, mean age 47±14.8, affected by RP followed in our department for more than three years. All the patients were submitted to a complete ophthalmological examination (BCVA measured on a Snellen chart, biomicroscopy, applanation tonometry, lens status evaluation, ophthalmoscopic fundus examination), OCT, Elettroretinogram (ERG) and Visual Evoked Potential (VEP). OCT measurements (Stratus OCT; Carl Zeiss Meditec GmbH, Oberchen, Germany) of the central macular thickness were made with fast macular thickness protocol. The results of the OCT scanning were analyzed with a standardized method according to Chan et al.
In our study 54 eyes, mean BCVA 0.9±0.1, mean foveal thickness 197.7±9.9, did not present macular abnormalities. Sixty eyes present CME, with a mean visual acuity of 0.7±0.2 and mean foveal thickness of 287.3±64.3µ. We found the most significant visual impairment in the last two groups. In fact, 24 eyes affected by vitreoretinal traction, showed a mean BCVA of 0.30±0.4 and a mean foveal thickness of 235.5±69.4 µ; 42 eyes present retinal thinning with a mean BCVA of 0.3±0.3 and mean foveal thickness of 126.1±28.4µ. We had further observed retinal thinning (mean age 52.1±13.6 years) and vitreoretinal traction (mean age 50.8±8.7 years) in older patients. No macular abnormalities and CME were found in patients with a mean age of 31.4±8.7 years and 43.1±17.4 years respectively.
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