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A. A. Ventura, S. Sharma, K. Sayanagi, P. K. Kaiser; Comparison of Retinal Thickness Measurements in Patients With Wet AMD Between Two 3D Fourier Domain Optical Coherence Tomography (OCT) Devices and Conventional Time Domain OCT. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2232.
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© ARVO (1962-2015); The Authors (2016-present)
To compare retinal thickness measurements using the Stratus time domain optical coherence tomography (OCT) and two commercially available 3D Fourier Domain OCT (FDOCT) devices in patients with choroidal neovascularization (CNV) due to age-related macular degeneration (AMD).
A prospective study was performed on 25 eyes with CNV secondary to AMD. Diagnostic imaging was done with Stratus OCT III (Carl Zeiss Meditec) and 2 FDOCT devices: a) SOCT Copernicus (Reichert/Optopol), b) 3D-OCT 1000 (Topcon). Automated measurements as well as manual central retinal thickness measurements were compared.
3D scan thickness measurements were similar on both the FDOCT devices and differed significantly from the fast macular thickness map on Stratus OCT III. Thickness measurements from the six line asterix scan were found to be similar on the FDOCT devices, but differed from Stratus. Thickness measurements from the 15 line asterix scan were found to be more similar to thickness measurements from the 3D cube scan than the six line asterix scan. Of all of the scan protocols, 3D scan was found to have the strongest correlation with manual central retinal thickness measurements.
As the number of lines used in the radial scan increases, accuracy of the retinal map also increases. The difference in the retinal thickness measurements between the FDOCT devices and Stratus is likely due to the long scan acquisition time on the Stratus.
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