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M. Takahashi, S. Kishi; Cystoid Macular Edema in Age-Related Macular Degeneration With Subfoveal Choroidal Neovascularization. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2245.
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Cystoid macular edema (CME) is a cause of decreased vision in age-related macular degeneration (AMD). We examined the incidence of CME among the subtypes of AMD using optical coherence tomography (OCT).
151 eyes of 151 patients with AMD who referred to Gunma University Hospital from January to December 2005 were recruited. The patients were subdivided to 69 eyes with typical AMD (type 1 CNV 29 eyes, type 2 CNV 40 eyes), 76 eyes with polypoidal choroidal vasculopathy (PCV) and 8 eyes with retinal angiomatous proliferation(RAP) by fluorescein angiography, indocyanine green angiography and OCT. CME was examined using OCT in each groups.
CME was observed in 34 eyes (22.5%) of all 151 eyes. Among the subtypes of exudative AMD, CME was present in 17 (24.6%) of 69 eyes with typical AMD, 9 (11.8%) of 76 eyes with PCV and 8(100%) of 8 eyes with RAP. Within typical AMD with subfoveal CNV, CME was observed in 4 (13.8%) of 29 eyes with type 1 CNV and 13 (32.5%) of 40 eyes with type 2 CNV. The mean visual acuity was 0.16 in the 34 eyes with CME, which was significantly poor than 117 eyes without CME whose visual acuity was 0.33(p<0.05).
CME was prevalent in eyes with type 2 CNV and RAP. In exudative AMD, visual acuity tends to be poor in case of associated CME.
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