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N. Omid, M. Farid, W. Chamberlain, A. Lin, R. F. Steinert; Comparison of Higher-Order Corneal Aberrations: Conventional Penetrating Keratoplasty vs. Femtosecond Laser Keratoplasty vs. DSEK. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2320.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate higher-order anterior corneal aberrations between three different keratoplasty techniques: conventional penetrating keratoplasty, femtosecond laser keratoplasty with a "zig-zag" pattern incision, and descemet stripping endothelial keratoplasty (DSEK).
Anterior corneal higher-order aberrations of four eyes of four patients who had conventional penetrating keratoplasty, five eyes of five patients who had femtosecond laser keratoplasty with a "zig-zag" pattern incision, and four eyes of four patients who had DSEK were compared using Zernike polynomial values obtained from Pentacam corneal topography. Mean Zernike polynomial values for 3rd to 8th order aberrations from each keratoplasty technique was compared for statistical significance using student T test. Both conventional penetrating keratoplasty and femtosecond laser keratoplasty were performed with a 24-bite running suture technique.
In this small series to date, there was a statistically significant lower amount of coma when comparing the mean Zernike values of the femtosecond laser "zig-zag" incision pattern keratoplasty (2.2042) and DSEK (0.9608) to conventional penetrating keratoplasty (3.5254) six-months to two years postoperatively. There was no statistically significant difference when comparing spherical aberrations or other higher (4th to 8th order) aberrations of the anterior cornea between the three different keratoplasty techniques.
Preliminary results suggest that when evaluating anterior corneal higher-order aberrations, the femtosecond laser keratoplasty "Zig-Zag" pattern keratoplasty and DSEK lead to decreased coma compared to conventional penetrating keratoplasty. Analysis of more cases is ongoing.
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