May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
The Use of Anterior Segment Optical Coherence Tomography in Descemet’s Stripping Endothelial Keratoplasty to Predict Ultimate Success or Failure in the Early Post-Operative Period
Author Affiliations & Notes
  • C. Y. Shih
    Ophthalmology, New York Eye and Ear Infirmary, New York, New York
  • P. Palmiero
    Ophthalmology, New York Eye and Ear Infirmary, New York, New York
  • D. Ritterband
    Ophthalmology, New York Eye and Ear Infirmary, New York, New York
  • J. Chelnis
    New York Medical College, Valhalla, New York
  • G. Papachristou
    Ophthalmology,
    New York Medical College, Valhalla, New York
  • R. Ritch
    Ophthalmology, New York Eye and Ear Infirmary, New York, New York
  • Z. Sbeity
    Ophthalmology, New York Eye and Ear Infirmary, New York, New York
  • J. Patel
    Ophthalmology, New York Eye and Ear Infirmary, New York, New York
  • J. Seedor
    Ophthalmology, New York Eye and Ear Infirmary, New York, New York
  • Footnotes
    Commercial Relationships  C.Y. Shih, None; P. Palmiero, None; D. Ritterband, None; J. Chelnis, None; G. Papachristou, None; R. Ritch, None; Z. Sbeity, None; J. Patel, None; J. Seedor, None.
  • Footnotes
    Support  Supported by Ephrain and Catherine Gildor Research Fund of the New York Glaucoma Research Foundation, The Educational Foundation of America, Westport CT
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 2321. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      C. Y. Shih, P. Palmiero, D. Ritterband, J. Chelnis, G. Papachristou, R. Ritch, Z. Sbeity, J. Patel, J. Seedor; The Use of Anterior Segment Optical Coherence Tomography in Descemet’s Stripping Endothelial Keratoplasty to Predict Ultimate Success or Failure in the Early Post-Operative Period. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2321. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose:
 

To determine the utility of Slit Lamp Optical Coherence Tomography (SL-OCT) to predict donor lenticle viability in Descemet’s Stripping Endothelial Keratoplasty (DSEK).

 
Methods:
 

58 DSEK’s performed by two surgeons (JAS and DCR) from March 1 2006 until September 2007 that had SL-OCT were reviewed. Lenticle and host cornea thickness was measured by SL-OCT when possible at 1 week, 1 month, 2 months, and greater than 2 months depending on the post-operative follow-up. Successful DSEK surgery was defined as having an attached, clear and compact lenticle without clinical evidence of endothelial decompensation, (≥2+) stromal thickening, or opacification.

 
Results:
 

58 DSEK eyes had at least one or more SL-OCT performed. 13 eyes had SL-OCT at one week, 10 were eventually successful and 3 were failures. Of the 10 successes the donor lenticle thickness ranged from165µ -312µ. The donor lenticle range for the 3 failures was 532µ -687µ.17 eyes that had SL-OCT at one month, 13 were ultimately successful and four were failures. Of the 13 successful DSEKs, 12/13 (92%) had a donor lenticle thickness of 350µ or less as measured by SL-OCT at one month. Of the 4 failed DSEKs, all had donor lenticle thickness of 375µ or more as measured at one month. The lenticle thickness range was 161µ -343µ, with one outlier at 495 in the 13 successful DSEK’s. The lenticle thickness range was 375µ -720 µ in the 4 failed DSEK’s.16 eyes had SL-OCT at two months, 12 were ultimately successful and 4 were failures. The range of lenticle thickness was 172µ -330µ for success and was 410µ-790µ in the failures.

 
Conclusions:
 

SL-OCT may be a valuable tool to predict DSEK success in attached lenticles within the first month of surgery. DSEK lenticle thickness of 350µ or less at one month had a predictability of success of greater than 90%. However further studies using intraoperative pachymetry to determine perioperative lenticle thickness may be required.  

 
Keywords: imaging/image analysis: clinical • cornea: clinical science • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×