May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Depth of Focus for Different Aberration Patterns Using an Adaptive-Optics Vision Simulator
Author Affiliations & Notes
  • P. A. Piers
    Applied Research, AMO Groningen, Groningen, The Netherlands
  • S. Manzanera
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
  • H. Weeber
    Applied Research, AMO Groningen, Groningen, The Netherlands
  • A. Mira
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
  • C. Canovas
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
  • P. Artal
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
  • Footnotes
    Commercial Relationships  P.A. Piers, Advanced Medical Optics, E; S. Manzanera, Advanced Medical Optics, C; H. Weeber, Advanced Medical Optics, E; A. Mira, Advanced Medical Optics, C; C. Canovas, Advanced Medical Optics, C; P. Artal, Advanced Medical Optics, C.
  • Footnotes
    Support  MEC_FIS2004-2153 (Spain)
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 2420. doi:
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      P. A. Piers, S. Manzanera, H. Weeber, A. Mira, C. Canovas, P. Artal; Depth of Focus for Different Aberration Patterns Using an Adaptive-Optics Vision Simulator. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2420.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To use an adaptive optics vision simulator (AOVS) to explore the impact of different aberration patterns on subjective depth of focus (DOF) determined using through-focus reading acuity. These tests will also be used to examine the suitability of optical metrics for predicting subjective DOF.

Methods: : An AOVS was constructed that allows us to simultaneously manipulate the effective ocular wavefront aberration and measure the resulting visual performance through different object vergences. Simulator testing was performed in white light on 3 subjects with a 4.8 mm pupil and paralyzed accommodation. DOF was determined in each subject for 6 cases of aberration: 1) the subject’s natural aberration pattern; 2) all aberrations corrected; 3) positive spherical aberration of 0.22 µm, 4) negative spherical aberration of 0.22 µm; 5) vertical coma of 0.22µm; and 6) astigmatism at 45° of 0.22µm. Reading acuity was determined for each of the 6 cases at best focus. Subsequently, subjective DOF was evaluated for these cases by determining the positive and negative defocus range for which the subject had acceptable reading acuity for a letter size twice that of their peak acuity. The ocular wavefront aberration was recorded at each focus position and used to determine MTF for corresponding spatial frequencies as well as MTF volume and encircled energy, thus enabling a comparison of objective DOF and subjective DOF.

Results: : Correcting all of the monochromatic aberrations of the eye decreased DOF. Differences in DOF were measured for the 4 different cases with similar RMS values. A comparison of optical DOF and subjective DOF showed similar trends for the 6 cases, but MTF volume is not a strong predictor of subjectively determined DOF using reading acuity. MTF values at the selected letter sizes are better optical predictors of DOF.

Conclusions: : Using an AOVS it was determined that inducing different types of higher-order aberration patterns results in different measured values of subjectively measured DOF. An AOVS is a powerful tool that can be used to investigate the optical factors that contribute to subjective DOF.

Keywords: aberrations • optical properties • refractive surgery: optical quality 
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