May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Effects of Ethyl Alcohol on Visual Function
Author Affiliations & Notes
  • A. Weber
    Ophthalmology Department, University Hospital Aachen, Aachen, Germany
  • N. Plange
    Ophthalmology Department, University Hospital Aachen, Aachen, Germany
  • C. Rennings
    Ophthalmology Department, University Hospital Aachen, Aachen, Germany
  • M. Kaup
    Ophthalmology Department, University Hospital Aachen, Aachen, Germany
  • J. Huth
    Ophthalmology Department, University Hospital Aachen, Aachen, Germany
  • P. Wolter
    Ophthalmology Department, University Hospital Aachen, Aachen, Germany
  • G. Roessler
    Ophthalmology Department, University Hospital Aachen, Aachen, Germany
  • T. Kirschkamp
    Ophthalmology Department, University Hospital Aachen, Aachen, Germany
  • A. Remky
    Ophthalmology Department, University Hospital Aachen, Aachen, Germany
  • Footnotes
    Commercial Relationships  A. Weber, None; N. Plange, None; C. Rennings, None; M. Kaup, None; J. Huth, None; P. Wolter, None; G. Roessler, None; T. Kirschkamp, None; A. Remky, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 2541. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      A. Weber, N. Plange, C. Rennings, M. Kaup, J. Huth, P. Wolter, G. Roessler, T. Kirschkamp, A. Remky; Effects of Ethyl Alcohol on Visual Function. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2541. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : To test the effect of ethyl alcohol on visual function in normal subjects.

Methods: : In 12 normal subjects (age: 27-43 yr; 4 male, 8 female), Frequency Doubling Perimetry (FDT) and Short-wavelength Automated Perimetry (SWAP) was performed before and 60 min after oral intake of 80 ml 40 vol% ethyl alcohol. Mean deviation (MD) and pattern standard deviation (PSD) were evaluated. Additionally, systemic blood pressure, heart beat, intraocular pressure (IOP), and blood alcohol concentration were assessed. Statistical analysis was performed using a paired t-test (Statview).

Results: : In FDT, mean deviation decreased significantly from 3.86 ± 0.9 db before to - 0.49 ± 1.9 after ethyl alcohol intake (p= 0.007), whereas PSD did not change significantly (p = 0.70). In SWAP, neither MD nor PSD showed significant changes after alcohol ingestion (p = 0.94 and p = 0.62, respectively). Mean IOP decreased from 12 ±2 mmHg before to 11 ± 2 mmHg after alcohol application (p= 0.01). Neither systemic systolic nor diastolic blood pressure showed significant changes (p=0.20 and 0.70, respectively). Mean blood alcohol concentration was 0.38 ± 0.16 g/l.

Conclusions: : Our results show a significant decrease in mean deviation in FDT after alcohol consumption and a slight increase in PSD indicating a general depression in retinal sensitivity with no particular presence of focal defects. Interestingly, in SWAP no changes were detectable. Moreover, our results indicate that low levels of blood alcohol might lead to an IOP reduction.

Keywords: visual fields 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×