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G. Gazzard, L. Lim, A. Kotecha, Y.-H. Chan, A. Fong, S.-M. Saw; Corneal Hysteresis and Myopia in Chinese Children. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2600.
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Corneo-scleral properties may determine susceptibility to myopia and corneal hysteresis is a novel measure of corneal biomechanical properties. We thus assessed the associations between refraction and corneal hysteresis determined with the Reichert Ocular Response Analyser (Reichert ORA; Reichert Ophthalmic Instruments, Depew, New York, USA) in Singaporean children.
A subset of schoolchildren from the Singapore Cohort Study of Myopia (SCORM) was recruited for the study. Corneal hysteresis (CH), corneal resistance factor (CRF) and central corneal thickness (CCT) measurements were obtained using the Reichert ORA without topical anaesthesia and before cycloplegia. Spherical equivalent refraction was assessed by cycloplegic refraction with an autokeratorefractometer (model RK5; Canon, Inc. Ltd., Tochigiken, Japan), axial length assessed by contact ultrasound A-scan biometry and Goldmann and non-contact air-puff tonometry were measured.
271 eyes of 271 subjects, mean age 14.0 ± 0.89 years, were included, of which 138 were male (50.9%) and the majority Chinese (186, 68.6%). Mean central corneal thickness was 579 µm (± 34; 495 - 698); Corneal hysteresis 11.8 mmHg (±1.6; 6.9 - 16.5); Corneal resistance factor 11.8mmHg (± 1.7; 7.8 - 16.8); Spherical equivalent -2.35D (± 2.49; -9.85 to +4.38) and Axial length 24.52mm (±1.15; 21.11 - 28.78). CH, CRF and CCT were normally distributed. CH was significantly correlated with CCT and CRF. CH and CRF did not vary significantly with age, sex, race or refractive error. CCT did not vary with age, sex or refractive error but was significantly higher in Chinese than Indian subjects.
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