May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Corneal Hysteresis and Myopia in Chinese Children
Author Affiliations & Notes
  • G. Gazzard
    Glaucoma Research, Institute of Ophthalmology, London, United Kingdom
    Moorfields Eye Hospital, London, United Kingdom
  • L. Lim
    Singapore National Eye Centre, Singapore, Singapore
  • A. Kotecha
    Glaucoma Research, Institute of Ophthalmology, London, United Kingdom
    City University, London, United Kingdom
  • Y.-H. Chan
    Singapore Eye Research Institute, Singapore, Singapore
  • A. Fong
    Singapore National Eye Centre, Singapore, Singapore
  • S.-M. Saw
    Singapore Eye Research Institute, Singapore, Singapore
  • Footnotes
    Commercial Relationships  G. Gazzard, None; L. Lim, None; A. Kotecha, None; Y. Chan, None; A. Fong, None; S. Saw, None.
  • Footnotes
    Support  National Medical Research Council, NMRC/0975/2005
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 2600. doi:
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    • Get Citation

      G. Gazzard, L. Lim, A. Kotecha, Y.-H. Chan, A. Fong, S.-M. Saw; Corneal Hysteresis and Myopia in Chinese Children. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2600.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Corneo-scleral properties may determine susceptibility to myopia and corneal hysteresis is a novel measure of corneal biomechanical properties. We thus assessed the associations between refraction and corneal hysteresis determined with the Reichert Ocular Response Analyser (Reichert ORA; Reichert Ophthalmic Instruments, Depew, New York, USA) in Singaporean children.

Methods: : A subset of schoolchildren from the Singapore Cohort Study of Myopia (SCORM) was recruited for the study. Corneal hysteresis (CH), corneal resistance factor (CRF) and central corneal thickness (CCT) measurements were obtained using the Reichert ORA without topical anaesthesia and before cycloplegia. Spherical equivalent refraction was assessed by cycloplegic refraction with an autokeratorefractometer (model RK5; Canon, Inc. Ltd., Tochigiken, Japan), axial length assessed by contact ultrasound A-scan biometry and Goldmann and non-contact air-puff tonometry were measured.

Results: : 271 eyes of 271 subjects, mean age 14.0 ± 0.89 years, were included, of which 138 were male (50.9%) and the majority Chinese (186, 68.6%). Mean central corneal thickness was 579 µm (± 34; 495 - 698); Corneal hysteresis 11.8 mmHg (±1.6; 6.9 - 16.5); Corneal resistance factor 11.8mmHg (± 1.7; 7.8 - 16.8); Spherical equivalent -2.35D (± 2.49; -9.85 to +4.38) and Axial length 24.52mm (±1.15; 21.11 - 28.78). CH, CRF and CCT were normally distributed. CH was significantly correlated with CCT and CRF. CH and CRF did not vary significantly with age, sex, race or refractive error. CCT did not vary with age, sex or refractive error but was significantly higher in Chinese than Indian subjects.

Keywords: myopia 
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