May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Myopia Prevention With 0.025% Atropine Solution in Premyopia Children
Author Affiliations & Notes
  • P.-C. Wu
    Ophthalmology, Chang Gung Memorial Hospital, Kaohsiung Hsien, Taiwan
  • P.-C. Fang
    Ophthalmology, Chang Gung Memorial Hospital, Kaohsiung Hsien, Taiwan
  • Footnotes
    Commercial Relationships  P. Wu, Pei-Chang Wu, P; P. Fang, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 2601. doi:https://doi.org/
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      P.-C. Wu, P.-C. Fang; Myopia Prevention With 0.025% Atropine Solution in Premyopia Children. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2601. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate the efficacy of 0.025% atropine solution for prevention of myopia in premyopia children.

Methods: : Retrospective case-control study.Fivety-two children (3-12 year-old) children with spherical refractive status range between +0.75 and -0.75D(which defined as premyopia), cylinder refractive status less than -2D, without amblyopia, who had received 0.025% atropine eyedrop once at night or no treatment after regular follow-up for one year at Chang Gung Memorial Hospital(Kaohsiung, Taiwan) from 2004 to 2007, were enrolled.

Results: : Twenty six children (average age 6.7 y/o) were in 0.025% atropine group and 26 children (average age 6.8 y/o) in control group. Mean spherical refraction progression in the 0.025% atropine group was -0.02 +/- 0.50 D/year, significantly lower than control group which was -0.69 +/- 0.46 D/year.(p<0.01)

Conclusions: : Topical 0.025% atropine eyedrop administration at bedtime regularly has effect on prevention myopia onset in premyopic school-aged children for one year period.

Keywords: myopia • clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials 
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