May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Vitrectomy for Diabetic Macular Edema: Long Term Results
Author Affiliations & Notes
  • G. Bertoldo
    Theia - Fondazione per l'Oftalmologia, Verona, Italy
  • E. Gusson
    Theia - Fondazione per l'Oftalmologia, Verona, Italy
  • G. Panozzo
    Theia - Fondazione per l'Oftalmologia, Verona, Italy
  • Footnotes
    Commercial Relationships  G. Bertoldo, None; E. Gusson, None; G. Panozzo, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 2715. doi:https://doi.org/
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      G. Bertoldo, E. Gusson, G. Panozzo; Vitrectomy for Diabetic Macular Edema: Long Term Results. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2715. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : The"VItrectomy for Diabetic macular Edema" (VIDE) Study has the purpose to estabilish the role of vitrectomy in changing the natural course of diffuse non tractional diabetic macular edema.

Methods: : In this phase II multicentric prospective clinical trial we have analized 37 eyes of 32 patients with chronic non tractional cystoid diabetic macular edema who underwent pars plana vitrectomy associated (75%) or not with peeling of internal limiting membrane. Patients were followed for 28 to 60 months, with a mean follow-up of 38.5 months. Main outcomes were visual acuity measured by Snellen chart and central retinal thickness and retinal volume measured by Optical Coherence Tomography.

Results: : Mean visual acuity improved from 0,22 preoperatively to 0,34 at the end of follow-up. Visual acuity remained unchanged in 52% of the patients, decreased of 2 or more lines in 12%, improved of 2 or more lines in 36% and of 4-6 lines in 16%. Mean central retinal thickness measured by OCT decreased from 413 µ preoperatively to 291 µ postoperatively, with an improvement in 84% of the eyes and absence of edema at the end of follow-up in 44%. Macular volume decreased from 9,81 mm3 to 8,81 mm3, with an improvement in 60% of the eyes and absence of edema at the end of follow-up in 24%.

Conclusions: : Vitrectomy for diabetic macular edema is a procedure still under investigation but these data demonstrate that may be effective in reducing non tractional diabetic macular edema in the long term.

Keywords: vitreoretinal surgery • diabetic retinopathy • vitreous 
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