May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Pattern Scan Laser System vs. Conventional Photocoagulation System: Electroretinogram Changes After Treatment
Author Affiliations & Notes
  • S. E. Vera-Rodriguez
    Retina, Asociacion para Evitar la Ceguera en Mex, Mexico DF, Mexico
  • R. Velez-Montoya
    Retina, Asociacion para Evitar la Ceguera en Mex, Mexico DF, Mexico
  • M. L. Lopez-Ramos
    Retina, Asociacion para Evitar la Ceguera en Mex, Mexico DF, Mexico
  • O. Alvarez-Verduzco
    Retina, Asociacion para Evitar la Ceguera en Mex, Mexico DF, Mexico
  • M. A. Martinez-Castellanos
    Retina, Asociacion para Evitar la Ceguera en Mex, Mexico DF, Mexico
  • C. C. Gonzalez-Mijares
    Retina, Asociacion para Evitar la Ceguera en Mex, Mexico DF, Mexico
  • J. L. Guerrero-Naranjo
    Retina, Asociacion para Evitar la Ceguera en Mex, Mexico DF, Mexico
  • J. M. JImenez-Sierra
    Retina, Asociacion para Evitar la Ceguera en Mex, Mexico DF, Mexico
  • V. Morales-Canton
    Retina, Asociacion para Evitar la Ceguera en Mex, Mexico DF, Mexico
  • H. Quiroz-Mercado
    Retina, Asociacion para Evitar la Ceguera en Mex, Mexico DF, Mexico
  • Footnotes
    Commercial Relationships  S.E. Vera-Rodriguez, None; R. Velez-Montoya, None; M.L. Lopez-Ramos, None; O. Alvarez-Verduzco, None; M.A. Martinez-Castellanos, None; C.C. Gonzalez-Mijares, None; J.L. Guerrero-Naranjo, None; J.M. JImenez-Sierra, None; V. Morales-Canton, None; H. Quiroz-Mercado, None.
  • Footnotes
    Support  NCT00563043
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 2766. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      S. E. Vera-Rodriguez, R. Velez-Montoya, M. L. Lopez-Ramos, O. Alvarez-Verduzco, M. A. Martinez-Castellanos, C. C. Gonzalez-Mijares, J. L. Guerrero-Naranjo, J. M. JImenez-Sierra, V. Morales-Canton, H. Quiroz-Mercado; Pattern Scan Laser System vs. Conventional Photocoagulation System: Electroretinogram Changes After Treatment. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2766. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : To compare electrorretinographic changes after panretinal photocoagulation (PRP) with conventional laser vs the Pattern Scan Laser system (PaScaL)

Methods: : A prospective, interventional and comparative study was performed in patients with severe non-proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR) without evidence of macular edema, and without previous laser treatment or anti-angiogenic drug therapy. PRP with conventional laser was performed in the right eye (OD) and with PaScaL in the left eye (OS); the eye to be treated first was assigned in a randomized fashion. PRP was performed in two sessions of 750 burns with an interval of 2 weeks. Best corrected visual acuity (BCVA) measurement and electrorretinogram (ERG) were performed in all patients at baseline and day 28. All t-paired tests were two-tailed with alpha=0.05.

Results: : Thirty eyes of 15 patients were included. Baseline BCVA was 42 letters (range: 23 to 55) in OD and 43 letters (range: 35 to 55) in OS. BCVA at 28 day was 30 letters (range: 24-51) in OD and 40 letters (range: 27-49) in OS. The a-wave decreased 59.01±12.53 µV (p: 0.0005) in OD and increased 10.35±16.72 µV (p: 0.9002) in OS. The b-wave decreased 200.94±164.73 µV (p: 0.0526) in OD and 91.48±3.19 µV (p: 0.5228) in OS. The implicit time increased 11.52±1.13 msec (p: 0.1208) in OD and 2.88±3.77 msec (p: 0.5851) in OS. Statistical significant differences were found in a-wave and b-wave of OD when final and initial amplitude were compared.

Conclusions: : We observed decreased statistically significant of a-wave in the conventional laser and increased no statistically significant in the PaScaL system. The b-wave decreased statistically significant in the conventional system and no statistically significant in the PaScaL system. The implicit time increased in both systems without statistically significant differences.

Clinical Trial: : www.clinicaltrials.gov NCT00563043

Keywords: laser • diabetic retinopathy 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×