May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Pattern-Scan Laser System vs. Conventional Photocoagulation: Changes in Macular Thickness After Treatment
Author Affiliations & Notes
  • M. d. Lopez
    Retina, Asociacion para evitar la ceguera en Mexico, Mexico City, Mexico
  • R. Velez-Montoya
    Retina, Asociacion para evitar la ceguera en Mexico, Deleg. Coyoacan, Mexico
  • S. Vera-Rodriguez
    Retina, Asociacion para evitar la ceguera en Mexico, Deleg. Coyoacan, Mexico
  • M. Martinez-Castellanos
    Retina, Asociacion para Evitar la Ceguera en Mexico, Mexico City, Mexico
  • O. Burgos-Vejar
    Retina, Asociacion para evitar la ceguera en Mexico, Deleg. Coyoacan, Mexico
  • C.-C. Gonzalez-Mijares
    Retina, Asociacion para evitar la ceguera en Mexico, Mexico City, Mexico
  • J. Guerrero-Naranjo
    Retina, Asociacion para evitar la ceguera en Mexico, Deleg. Coyoacan, Mexico
  • D. Ochoa-Contreras
    Retina, Asociacion para evitar la ceguera en Mexico, Deleg. Coyoacan, Mexico
  • V. Morales-Canton
    Retina, Asociacion para evitar la ceguera en Mexico, Deleg. Coyoacan, Mexico
  • H. Quiroz-Mercado
    Retina, Asociacion para evitar la ceguera en Mexico, Deleg. Coyoacan, Mexico
  • Footnotes
    Commercial Relationships  M.D. Lopez, None; R. Velez-Montoya, None; S. Vera-Rodriguez, None; M. Martinez-Castellanos, None; O. Burgos-Vejar, None; C. Gonzalez-Mijares, None; J. Guerrero-Naranjo, None; D. Ochoa-Contreras, None; V. Morales-Canton, None; H. Quiroz-Mercado, None.
  • Footnotes
    Support  NCT00563628
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 2768. doi:https://doi.org/
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    • Get Citation

      M. d. Lopez, R. Velez-Montoya, S. Vera-Rodriguez, M. Martinez-Castellanos, O. Burgos-Vejar, C.-C. Gonzalez-Mijares, J. Guerrero-Naranjo, D. Ochoa-Contreras, V. Morales-Canton, H. Quiroz-Mercado; Pattern-Scan Laser System vs. Conventional Photocoagulation: Changes in Macular Thickness After Treatment. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2768. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To measure the difference in central macular thickness (CMT) and macular volume (MV) by optic coherence tomography (OCT), before and after panretinal photocoagulation (PRP) with Pattern Scan Laser (PaScaL) vs conventional laser, in patients with severe non-proliferative diabetic retinopathy (SNPDR) and proliferative diabetic retinopathy (PDR)

 
Methods:
 

We designed a prospective, interventional and comparative study, where we included patients with SNPDR or PDR without clinical macular edema, previous laser treatment or anti-angiogenic drug therapy. PRP was performed in two sessions of 750 burns each, with an interval of 2 weeks, always with conventional laser in the right eye and PaScaL system in the left eye. We measured best corrected visual acuity (BCVA), CMT and MV by OCT (OCT3, Carl Zeiss) at baseline and day 28. All t-paired tests were two-tailed with alpha=0.05

 
Results:
 

We included 15 patients (30 eyes), 16 eyes with PDR. All measures are summarized in Table 1. Significant differences were found in the following comparisons between baseline versus the 28th day: CMT left eye (p=0.04); MV right eye (p=0.01) and left eye (p=0.006); BCVA right eye (p=0.05) and left eye (p=0.03)

 
Conclusions:
 

Even though it is a preliminary study in which only five cases were compared, we observed that in both eyes, CMT and MV increased, while ETDRs decreased  

 
Clinical Trial:
 

www.clinicaltrials.gov NCT00563628

 
Keywords: laser • diabetic retinopathy • edema 
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