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A. Ishibazawa, S. Igarashi, S. Ishiko, K. Hanada, O. Muramatsu, A. Yoshida; Central Corneal Thickness Measurement With Fourier-Domain Optical Coherence Tomography versus Ultrasonic Pachymetry. Invest. Ophthalmol. Vis. Sci. 2008;49(13):2817.
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To compare the accuracy and repeatability of Fourier-domain optical coherence tomography (FD-OCT) with ultrasound pachymetry in the measurement of central corneal thickness (CCT).
CCT was measured in 30 subjects (30 normal corneas) by the same examiner, using ultrasonic pachymeter and FD-OCT (RTVue-100, Optovue) with anterior segment adaptor.
Mean +/- SD CCT measured by FD-OCT was 533 +/- 37 microm. This was highly correlated (Pearson's coefficient = 0.971) with the mean thickness measured by ultrasound pachymetry (567 +/- 35 microm). The coefficients of variation were good and comparable at 8.0% for ultrasonic pachymetry and 3.4% for FD-OCT.
Our data showed that FD-OCT instrument provided measurements that were slightly but systematically lower than the measurements provided by ultrasonic pachymetry, which is currently the clinical gold standard method.
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