Abstract
Purpose: :
To compare the accuracy and repeatability of Fourier-domain optical coherence tomography (FD-OCT) with ultrasound pachymetry in the measurement of central corneal thickness (CCT).
Methods: :
CCT was measured in 30 subjects (30 normal corneas) by the same examiner, using ultrasonic pachymeter and FD-OCT (RTVue-100, Optovue) with anterior segment adaptor.
Results: :
Mean +/- SD CCT measured by FD-OCT was 533 +/- 37 microm. This was highly correlated (Pearson's coefficient = 0.971) with the mean thickness measured by ultrasound pachymetry (567 +/- 35 microm). The coefficients of variation were good and comparable at 8.0% for ultrasonic pachymetry and 3.4% for FD-OCT.
Conclusions: :
Our data showed that FD-OCT instrument provided measurements that were slightly but systematically lower than the measurements provided by ultrasonic pachymetry, which is currently the clinical gold standard method.
Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • anterior segment • imaging/image analysis: clinical