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Q. You, L. Xu, Y. Wang, J. B. Jonas; Prevalence of Tilted Optic Discs and the Relationship to Refractive Error: The Beijing Eye Study. Invest. Ophthalmol. Vis. Sci. 2008;49(13):3138.
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To determine the prevalence of tilted optic discs and their associations with ocular and general parameters in an adult Chinese population.
The Beijing Eye Study included 4439 subjects out of 5324 subjects invited to participate (response rate 83.4%) with an age of 40+ years. The present investigation consisted of 8594 (96.8%) eyes of 4324 (97.4%) subjects for whom readable fundus photographs of at least one eye were available. Main outcome parameter was the presence of tilted optic discs defined as small discs with an oblique orientation and oval disc shape without signs of pathology.
Tilted optic discs were detected in 155 (1.8% per eye,95% confidence interval: 1.6%, 2.0%) eyes of 108 subjects (60 women). The prevalence rate was 2.4% (95% confidence interval: 2.0%, 2.8%) per subject. In a logistic binary analysis, tilted optic discs were significantly associated with disc area (P<0.001), spherical refractive error (p<0.001) and astigmatism (p=0.025). They were statistically not associated with age (p=0.149), gender (p=0.274), intraocular pressure (p=0.173), nuclear cataract (p=0.644),cortical cataract (p=0.325), subcapsular cataract (p=0.209), visual field defects (p=0.072), and best corrected visual acuity (p=0.233).
Tilted optic discs are present in about 24 out of 1000 adult Chinese in Northern China. They are associated with spherical refractive error (myopia), astigmatism and small optic discs.
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