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N. Ishikawa, T. Miyamoto, S. Saika; Cell Adhesion on Intraocular Lenses of Various Materials in Japanese Patients. Invest. Ophthalmol. Vis. Sci. 2008;49(13):3337.
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To study the difference of cell adhesion by foreign-body reaction on intraocular lenses (IOLs) of various materials that were extracted from Japanese patients.
Extracted IOLs of PMMA (n = 271), soft acrylic material (n = 117), and slicone (n = 48) were studied. Samples were collected by the Japanese Society of Cataract and Refrcative Surgery. Each IOL was stained with hematoxylin and eosin and observed under light microscopy. The number of cells on the anterior surface of the optic was counted. The samples were grouped as IOLs extracted after 1 to 6, 6 to 12, 12 to 24 or over 24 months after implantation.
Cell adhesion on PMMA IOLs were significantly higher as compared with on silicone IOLs edxtracted 6 to 12 months post-implantation. There was no statistical difference of cell numbers on PMMA IOLs and on acrylic IOLs.
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