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S. Mizunoya, H. Kanai, Y. Kanaya, K. Ikeda, A. Hosoda, H. Abe, H. Kidahashi, M. Suzuki; Efficacy of Sub-Tenon Triamcinolone Acetonide to Prevent Macular Edema After Panretinal Photocoagulation for Proliferative Diabetic Retinopathy. Invest. Ophthalmol. Vis. Sci. 2008;49(13):3491.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the effectiveness of sub-tenon triamcinolone acetonide (STTA) in preventing macular edema after panretinal photocoagulation (PRP) for proliferative diabetic retinopathy.
Twenty milligrams of TA was injected into the posterior sub-tenon’s capsule before panretinal photocoagulation in 16 eyes of 10 patients (age, mean 55 years; range, 40 to 69 years) with proliferative diabetic retinopathy. Patients had a complete ophthalmic evaluation including visual acuity and optical coherence tomography (OCT) at baseline and at follow-up visits.
The follow-up period was >3 months in all eyes. The mean best-corrected visual acuity improved from 0.30 at baseline to 0.23 logMAR units at 3 month after STTA. The mean foveal thickness (FT) was 361±170 µm at baseline and 363±183 µm at 3 month. After 3 month, 5 eyes of 4 cases had a reduction of FT >20%, 8 eyes of 5 cases did not change (<±20%), and 3 eyes of 3 cases had an increase in the FT >20% compared to the baseline. No adverse side-effects were observed following TA.
Posterior sub-Tenon’s capsule injection of 20 mg TA performed before PRP for proliferative diabetic retinopathy may prevent the PRP-induced macular edema and a reduction of vision.
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