May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Ciliary Body Thickness, Refractive Error, and Axial Length in Adults
Author Affiliations & Notes
  • L. E. Ernst
    College of Optometry, The Ohio State University, Columbus, Ohio
  • L. T. Sinnott
    College of Optometry, The Ohio State University, Columbus, Ohio
  • M. D. Bailey
    College of Optometry, The Ohio State University, Columbus, Ohio
  • Footnotes
    Commercial Relationships  L.E. Ernst, None; L.T. Sinnott, None; M.D. Bailey, None.
  • Footnotes
    Support  NEI T35-EYO7151
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 3580. doi:
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      L. E. Ernst, L. T. Sinnott, M. D. Bailey; Ciliary Body Thickness, Refractive Error, and Axial Length in Adults. Invest. Ophthalmol. Vis. Sci. 2008;49(13):3580.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

A previous study reported increasing ciliary body thickness with increasing levels of myopia using ultrasound biomicroscopy. The purpose of this study was to determine the relationship between ciliary body thickness and refractive error in adults using the Zeiss VisanteTM Anterior Segment OCT.

 
Methods:
 

Thirty-five subjects between the ages of 20 and 39 years with varying refractive error (range: –8.53 to +3.13) were included in the analysis. Cycloplegic refractive error was measured using a Grand Sieko autorefractor, axial length was measured with the IOLMaster, and images of the nasal ciliary body where obtained through the sclera while the subject fixated on a peripheral target. Ciliary body measurements were taken 2 mm (CB2) posterior to the scleral spur. Multilevel regression models were used to define the relationship between ciliary body thickness, refractive error, and axial length.

 
Results:
 

The relationship between ciliary body thickness and refractive error was not linear; the quadratic term in refractive error was significant (p < 0.001), indicating that ciliary body thickness was greatest in those with low to moderate levels of myopia. Also, the relationship between ciliary body thickness and axial length was not linear; the quadratic term in axial length was significant (p = 0.003), indicating that ciliary body thickness was greatest at moderate values of axial length.

 
Conclusions:
 

The ciliary body is thicker in patients with of low to moderate myopia; in higher levels of myopia and the largest axial lengths, however, ciliary body thickness is similar to that found in emmetropia. Further studies are needed to determine if thicker ciliary bodies are related to the etiology of myopia and if differences in the etiology exist for low to moderate myopia as opposed to high myopia.  

 
Keywords: myopia • refractive error development • ciliary body 
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