Results of Scanning Peripheral Anterior Chamber Depth Analyzer and Associated Factors in a Population-Based Study in Southern Part of Japan: The Kumejima Study

Abstract

Purpose: : To evaluate the distribution of peripheral anterior chamber depth (PACD) in a population in a southern island of Japan and to analyze the relationship between PACD and other factors.

Methods: : 3762 persons participated (participation ratio 81.2%) from 40 years or older population of Kumejima Town. Reliable PACD measurements were obtained using scanning peripheral anterior chamber depth analyzer (SPAC) from 3,158 participants.

Results: : PACD was graded 1 to 12 automatically depend on the measurement value. The PACD grade averaged 7.5 +/- 2.2 (mean +/- standard deviation), and smaller in women (7.1 +/- 2.1) than men (7.9 +/- 2.1)(P<0.001). PACD grade was negatively correlated with age and refractive error, and was positively correlated with axial length, van Herick grading, and central anterior chamber depth (P<0.001). 295 subjects (9.3%) were diagnosed as possible angle closure and additional 379 (12.0%) were high risk of angle closure (S) by an automated diagnosis software builted in the SPAC.

Conclusions: : PACD grade obtained using SPAC in population in a southern island of Japan was significantly negatively correlated with age and refractive error, and was significantly positively correlated with axial length, van Herick grading, and central anterior chamber depth. A total of 21.3% of the population aged 40 years or older were found to be angle closure and its suspect by the SPAC analysis.

Keywords: clinical (human) or epidemiologic studies: risk factor assessment • imaging/image analysis: clinical • anterior chamber