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A. A. Kamdeu Fansi, H. Boisjoly, M. Chagnon, P. J. Harasymowycz; Combining Rim Area to Disc Area Asymmetry Ratio (Radaar) and Moorfields Classification for HRT III - Based Diagnosis of Glaucoma. Invest. Ophthalmol. Vis. Sci. 2008;49(13):3599.
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To determine the utility of combining rim area to disc area asymmetry ratio (RADAAR) and Moorfields Classification of HRT III on glaucoma diagnosis
460 subjects were included in this study. RADAAR values were calculated based on stereometric HRT II values by dividing the value of the smaller rim / disc area to the value of the greater rim / disc area. Gold-standard was clinical diagnosis of glaucomatous optic nerve damage. Main Outcome measures included Sensitivity, specificity values of single HRTIII-MFC test and combining HRTIII - RADAAR - MFC tests.
Range of results for HRTIII - MFC: Sensitivity =52.81%-74.77%; Specificity=63.43%-71.50%. Range of results for HRTIII - RADAAR - MFC: Sensitivity=43.17%-76.05%; Specificity=78.32%-86.56%.
By combining rim area to disc area asymmetry ratio (RADAAR) and Moorfields Classification (MFC), sensitivity and specificity changed. This may be useful when using HRTIII for the purpose of mass screening
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