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U. Oberheide, S. Schumacher, P. Bock, I. Imbschweiler, M. Fromm, A. Wegener, G. Gerten, A. Beineke, H. Lubatschowski; Femtosecond Lentotomy: Retinal Changes After Treatment of the Crystalline Lens With a 100 Khz Femtosecond Laser in Rabbits. Invest. Ophthalmol. Vis. Sci. 2008;49(13):3796.
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© ARVO (1962-2015); The Authors (2016-present)
One concept of regaining the elasticity of the lens material is the treatment of the lens by femtosecond laser pulses (femtosecond lentotomy). However the effect of the femtosecond laser pulses on retinal structures is only well investigated for corneal treatment.Our aim was to evaluate changes of the retinal layers after treatment of the crystalline lens in rabbits with high repetition femtosecond lasers.
We used an IMRA µJewel femtosecond laser with 100 kHz repetition rate to create microincisions in crystalline lenses of 10 rabbit eyes in vivo. Only one eye was treated leaving the other as control.The eyes were examined by histology (HE staining) to evaluate the influence of the femtosecond laser pulses on the retina as side effect of the treatment.
The histological examination reveals no degenerative or inflammatory changes of the retina. No thermal alterations of retinal layers due to the laser treatment are visible in the histological sections.
These preliminary results show that treating the crystalline lens with femtosecond laser pulses does not have harmful side effects on retinal structures. Therefore concerning retinal safety femtosecond lentotomy might be a reasonable tool for treatment of the crystalline lens.
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