May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Femtosecond Lentotomy: Changing the Crystalline Lens Tissue by High Repetition Rate Femtosecond Lasers
Author Affiliations & Notes
  • S. Schumacher
    Biomedical Optics Department, Laser Zentrum Hannover eV, Hannover, Germany
  • M. Fromm
    Biomedical Optics Department, Laser Zentrum Hannover eV, Hannover, Germany
  • P. Bock
    Institut für Pathologie, Tierärztliche Hochschule Hannover, Hannover, Germany
  • I. Imbschweiler
    Institut für Pathologie, Tierärztliche Hochschule Hannover, Hannover, Germany
  • A. Beineke
    Institut für Pathologie, Tierärztliche Hochschule Hannover, Hannover, Germany
  • G. Gerten
    Laserforum Köln eV, Cologne, Germany
  • H. Lubatschowski
    Biomedical Optics Department, Laser Zentrum Hannover eV, Hannover, Germany
  • U. Oberheide
    Laserforum Köln eV, Cologne, Germany
  • Footnotes
    Commercial Relationships  S. Schumacher, None; M. Fromm, None; P. Bock, None; I. Imbschweiler, None; A. Beineke, None; G. Gerten, None; H. Lubatschowski, Inventor, P; U. Oberheide, Inventor, P.
  • Footnotes
    Support  BMBF 13N8712 and BMBF 13N8709
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 3798. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      S. Schumacher, M. Fromm, P. Bock, I. Imbschweiler, A. Beineke, G. Gerten, H. Lubatschowski, U. Oberheide; Femtosecond Lentotomy: Changing the Crystalline Lens Tissue by High Repetition Rate Femtosecond Lasers. Invest. Ophthalmol. Vis. Sci. 2008;49(13):3798. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : According to Helmholtz’ theory of accommodation one of the mayor reasons for the development of presbyopia is the increasing sclerosis of the lens. One concept of regaining the elasticity of the lens tissue is the treatment of the lens by femtosecond laser pulses.

Methods: : Our aim was to evaluate changes of crystalline lenses due to the treatment with high repetition femtosecond lasers. We used an IMRA µJewel femtosecond laser with 100 kHz repetition rate to create microincisions in crystalline lenses of human autopsy eyes as well as in porcine and rabbit eyes. The treated eyes were analyzed using OCT and histological sections for detection of the cuts. Mechanical changes were analyzed with Fisher’s spinning test and a lens stretching device.

Results: : The cuts in the crystalline lenses were detectable with OCT. Histological sections show limited thermal and mechanical alteration of the interaction zone. The rotation experiments as well as the lens stretching experiments show an increase in flexibility for the treated lenses.

Conclusions: : Fs-laser induced cuts in the lens lead to a gain in lens flexibility. Due to the high repetition rate the treatment time could be decreased drastically compared to former investigations.

Keywords: presbyopia • accomodation • laser 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×