May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
The Interocular Amplitude Ratio of Flicker Electroretinogram Is a Strong Prognostic Indicator of Neovascularization in Central Retinal Vein Occlusion
Author Affiliations & Notes
  • H.-K. Kuo
    Ophthalmology, Chang Gung Memorial Hospital, Kaohsiung, Kaohsiung Hsien, Taiwan
  • M.-T. Kuo
    Ophthalmology, Chang Gung Memorial Hospital, Kaohsiung, Kaohsiung Hsien, Taiwan
  • P.-C. Wu
    Ophthalmology, Chang Gung Memorial Hospital, Kaohsiung, Kaohsiung Hsien, Taiwan
  • Y.-H. Chen
    Ophthalmology, Chang Gung Memorial Hospital, Kaohsiung, Kaohsiung Hsien, Taiwan
  • Footnotes
    Commercial Relationships  H. Kuo, None; M. Kuo, None; P. Wu, None; Y. Chen, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 3806. doi:https://doi.org/
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      H.-K. Kuo, M.-T. Kuo, P.-C. Wu, Y.-H. Chen; The Interocular Amplitude Ratio of Flicker Electroretinogram Is a Strong Prognostic Indicator of Neovascularization in Central Retinal Vein Occlusion. Invest. Ophthalmol. Vis. Sci. 2008;49(13):3806. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : to evaluate the prognostic value of flicker electroretinogram (ERG) in case of CRVO regarding the development of neovascularization (NV).

Methods: : Retrospectively review the data of scotopic flicker ERG of 69 CRVO patients. The fellow eye was treated as the normal control. 24 patients that had enough follow up to be adjusted as ischemia (I) or nonischemia (N) were treated as the study group.

Results: : In the control eyes, age statistically influenced the latency (p=0.018), but not the amplitude (p=0.756). In the study group, 10 eyes were ischemic and suffered from vitreous hemorrhage or neovascular glaucoma. Another 14 eyes were nonischemia. The latency value of I group located at both tails of normal data, but, the mean value of interocular latency difference (lesion eye and fellow eye) between I and N group was not statistically different. The interocular amplitude difference and amplitude ratio between I and N groups were statistically strongly different (p<0.000).

Conclusions: : The amplitude of flicker electroretinogram is a good prognostic indicator of neovascularization in central retinal vein occlusion.

Keywords: vascular occlusion/vascular occlusive disease • electroretinography: clinical • ischemia 
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