May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Choroidal Vascular Involvement in Patients With Acute Vogt-Koyanagi-Harada Disease
Author Affiliations & Notes
  • R. Messaoud
    Ophthalmology, Tahar Sfar University Hosp, Mahdia, Tunisia
  • S. Attia
    Ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
  • S. Zaouali
    Ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
  • B. Jelliti
    Ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
  • S. Jenzeri
    Ophthalmology, Tahar Sfar University Hosp, Mahdia, Tunisia
  • M. Khairallah
    Ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
  • Footnotes
    Commercial Relationships  R. Messaoud, None; S. Attia, None; S. Zaouali, None; B. Jelliti, None; S. Jenzeri, None; M. Khairallah, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 3887. doi:https://doi.org/
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      R. Messaoud, S. Attia, S. Zaouali, B. Jelliti, S. Jenzeri, M. Khairallah; Choroidal Vascular Involvement in Patients With Acute Vogt-Koyanagi-Harada Disease. Invest. Ophthalmol. Vis. Sci. 2008;49(13):3887. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To analyze choroidal vascular involvement in acute Vogt-Koyanagi-Harada (VKH) disease.

Methods: : The study included 13 consecutive patients (26 eyes) with acute VKH disease. All patients underwent a complete ophthalmic evaluation that included measurement of best-corrected visual acuity, slit-lamp examination, and dilated fundus examination with contact lenses. Fundus photography, fluorescein angiography, and indocyanine green (ICG) angiography were performed in all cases.

Results: : Eyes were affected as follows: choriocapillaris filling delay/defects (26; 100%), a decrease in the number of large choroidal vessels (10; 38.5%), perivascular leakage (24; 92.3%), areas of choroidal hyperfluorescence in the late phase of ICG angiography (20; 76.9%), and severe thrombosis of large choroidal vessels (2; 7.7%).

Conclusions: : Choroidal vasculopathy, with features of choroidal ischemia and vascular hyperpermeabilty, appears to be a prominent finding in patients with acute VKH disease. ICG angiography could be a useful tool in detecting and monitoring choroidal vasculopathy in patients with acute VKH disease.

Keywords: inflammation • choroid 
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