May 2008
Volume 49, Issue 13
ARVO Annual Meeting Abstract  |   May 2008
Posterior Vitreoschisis in Uveitis: A Prospective Study
Author Affiliations & Notes
  • D. R. Lucena
    Retina, Universidade Sao Paulo, Ribeirao Preto, Brazil
  • R. Jorge
    Retina, Universidade Sao Paulo, Ribeirao Preto, Brazil
  • L. R. Lucena
    Retina, Universidade Sao Paulo, Ribeirao Preto, Brazil
  • F. P. P. Almeida
    Retina, Universidade Sao Paulo, Ribeirao Preto, Brazil
  • A. L. P. Lucena
    Oftalmologia, UNAERP, Ribeirao Preto, Brazil
  • Footnotes
    Commercial Relationships  D.R. Lucena, None; R. Jorge, None; L.R. Lucena, None; F.P.P. Almeida, None; A.L.P. Lucena, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 3903. doi:
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      D. R. Lucena, R. Jorge, L. R. Lucena, F. P. P. Almeida, A. L. P. Lucena; Posterior Vitreoschisis in Uveitis: A Prospective Study. Invest. Ophthalmol. Vis. Sci. 2008;49(13):3903. doi:

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To verify the prevalence of posterior vitreoschisis in posterior focal uveitis and its relation to lesion size and localization, and secondary vitreous haze, and to classify the posterior vitreoschisis based on ecographic findings.

Methods: : All patients from the Department of Ophthalmology - University Hospital, Faculty of Medicine of Ribeirão Preto, University of São Paulo, with a diagnosis of posterior focal uveitis between 10 and 45-year-old were invited to participate in the study. Ophthalmic evaluation consisted of indirect ophthalmoscopy and B-scan ultrasound (10MHz).

Results: : One-hundred-and-thirty-one eyes of 131 patients were enrolled in the study. The prevalence of posterior vitreoschisis was 73.28%. Lesions with more than 2 DD size and with more than 2+/4+ vitreous haze were significantly associated with the development of posterior vitreoschisis (p=0.005 and p<0.001, respectively). No association was found between lesion localization and posterior vitreoschisis. It was possible to classify posterior vitreoschisis as type I-characterized by partial posterior vitreous detachment (PVD), type II-characterized by complete PVD, and type III-characterized by pseudocomplete PVD when the outer vitreoschisis layer stays attached to the inner limiting membrane of the retina.

Conclusions: : Occurrence of posterior vitreoschisis was positively related to lesion size and vitreous haze, and its location coincided with the posterior focal uveitis site, according to OLYS theory.

Keywords: uveitis-clinical/animal model • toxoplasmosis • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 

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