May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Light Absorption Properties of the Rabbit Corna Repeatedly Irradiated With UV Rays
Author Affiliations & Notes
  • C. Cejka
    Department of Ophthalmology for Children and Adults, Charles University of Prague, 2nd Faculty of Medicine, Prague 5, Czech Republic
    Department of Eye Histochemistry and Pharmacology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague 4, Czech Republic
  • V. Guryca
    Academy of Sciences of the Cech Republic, Institute of Macromolecular Chemistry, Prague 5, Czech Republic
  • J. Sirc
    Academy of Sciences of the Cech Republic, Institute of Macromolecular Chemistry, Prague 5, Czech Republic
  • T. Ardan
    Department of Eye Histochemistry and Pharmacology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague 4, Czech Republic
  • J. Michalek
    Academy of Sciences of the Cech Republic, Institute of Macromolecular Chemistry, Prague 5, Czech Republic
  • B. Brunova
    Department of Ophthalmology for Children and Adults, Charles University of Prague, 2nd Faculty of Medicine, Prague 5, Czech Republic
  • J. Cejkova
    Department of Eye Histochemistry and Pharmacology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague 4, Czech Republic
  • Footnotes
    Commercial Relationships  C. Cejka, None; V. Guryca, None; J. Sirc, None; T. Ardan, None; J. Michalek, None; B. Brunova, None; J. Cejkova, None.
  • Footnotes
    Support  Grant Agency of the Charles University of the Czech Republic 47/2006/C/2.LF
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 3915. doi:https://doi.org/
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    • Get Citation

      C. Cejka, V. Guryca, J. Sirc, T. Ardan, J. Michalek, B. Brunova, J. Cejkova; Light Absorption Properties of the Rabbit Corna Repeatedly Irradiated With UV Rays. Invest. Ophthalmol. Vis. Sci. 2008;49(13):3915. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Purpose of this study was to examine the light absorption properties of the cornea repeatedly irradiated with UVA or UVB rays.

Methods: : Adult New Zealand white rabbits were employed. In the first group of rabbits the corneas were irradiated with UVB rays (312 nm), in the second group with UVA rays (365 nm). In both groups of animals the irradiation took place once a day, a dose per day 1.01 J/cm2. Some animals of both groups were irradiated once, some other rabbits twice and the rest of rabbits three times. The animals were sacrificed the following day after the last irradiation. Absorbances of corneal centers (a circle of 6 mm diameter) of normal corneas (as controls) and irradiated corneas were measured over a range of 190-650 nm using a scanning spectrophotometer (HELIOSb 84021).

Results: : With the repeated UVB irradiation (not UVA irradiation) corneal light absorption was increasing together with the increase in corneal thickness (elevated hydration) and changes of corneal transparency.

Conclusions: : UVB rays (not UVA rays) changed corneal light absorption properties.

Keywords: cornea: basic science • radiation damage: light/UV • pathology: experimental 
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