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H. Takenaka, K. Hirooka, T. Baba, M. Mizote, M. Takagishi, F. Shiraga; Effect of Trabeculectomy on Intraocular Pressure Fluctuation With Postural Change in Eyes With Open-Angle Glaucoma. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4160.
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To investigate the effect of trabeculectomy on the intraocular pressure (IOP) fluctuations caused by the postural change in patients with open-angle glaucoma because the progression of visual field damage in open-angle glaucoma may be associated with IOP in the supine position and the magnitude of IOP elevation accompanying postural change.
Ten eyes of 10 patients with open-angle glaucoma who underwent trabeculectomy were studied. The IOP at the baseline and after trabeculectomy was measured in both sitting and supine positions. A pneumatonometer was used to measure the IOP in both sitting and supine position.
The mean IOP in the sitting position was 19.2 ± 4.7 mmHg at the baseline and 9.0 ± 3.2 mmHg after trabeculectomy (P < 0.05, paired t-test). The mean difference in IOP between the sitting and supine position was 3.9 ± 1.5 mmHg at the baseline and 1.9 ± 1.5 mmHg after trabeculectomy (P < 0.05, paired t-test).
Trabeculectomy might decrease not only the IOP in the sitting position but also the magnitude of IOP elevation associated with the postural change.
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