May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
The Assessment of Optical Coherence Tomography (OCT) as a Predictor of Visual Acuity in Diabetic Macular Oedema
Author Affiliations & Notes
  • L. Pelosini
    Ophthalmology, The Rayne Inst, St Thomas' Hospital, London, United Kingdom
  • J. Boyce
    Ophthalmology, The Rayne Inst, St Thomas' Hospital, London, United Kingdom
  • J. D. A. McHugh
    Ophthalmology, King's College Hospital, London, United Kingdom
  • M. Stanford
    Ophthalmology, The Rayne Inst, St Thomas' Hospital, London, United Kingdom
  • J. Marshall
    Ophthalmology, The Rayne Inst, St Thomas' Hospital, London, United Kingdom
  • Footnotes
    Commercial Relationships  L. Pelosini, None; J. Boyce, None; J.D.A. McHugh, None; M. Stanford, None; J. Marshall, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 4236. doi:https://doi.org/
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    • Get Citation

      L. Pelosini, J. Boyce, J. D. A. McHugh, M. Stanford, J. Marshall; The Assessment of Optical Coherence Tomography (OCT) as a Predictor of Visual Acuity in Diabetic Macular Oedema. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4236. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To investigate whether retinal structural integrity may be a prognostic indicator in cystoid macular oedema (CMO).

Methods: : The study was conducted at the Department of Ophthalmology, St Thomas’ Hospital, London. Institutional Ethics Committee approval was obtained (06/Q0702/175).127 patients underwent functional assessment (LogMAR, Bailey-Lovie charts, SLO microperimetry) and morphologic examination of the macular area with OCT/SLO imaging (OTI, Toronto). Structural integrity was measured evaluating the number, diameter and eccentricity of columns between cystoid spaces of CMO on axial and coronal OCT scans. The images were processed with an automated image analysis method.

Results: : LogMAR visual acuity (r=0.4, P<0.002), Bailey-Lovie acuity (r=0.68, P<0.0001) and contrast sensitivity (r=0.7, P<0.0008) correlated significantly with measures of tissue integrity on OCT scans. A significant inverse correlation was found between microperimetry values (r= -0.43, P<0.0001) and eccentricity of columns.

Conclusions: : Retinal structural integrity from OCT scans may be used as a predictor of final visual outcome in cystoid macular oedema.

Keywords: macula/fovea • diabetic retinopathy • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 
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