May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Variability Between Trained Experts Performing Hand-Drawn Segmentations of CirrusTm HD-OCT Scans
Author Affiliations & Notes
  • T. A. Abunto
    Carl Zeiss Meditec, Inc., Dublin, California
    Clinical Affairs,
  • T. Callan
    Carl Zeiss Meditec, Inc., Dublin, California
    Clinical Affairs,
  • P. Stetson
    Carl Zeiss Meditec, Inc., Dublin, California
    Advanced Development,
  • M. Durbin
    Carl Zeiss Meditec, Inc., Dublin, California
    Advanced Development,
  • M. Wieland
    Ophthalmology, Northern California Retina and Vitreous Associates, Mountain View, California
  • N. M. Bressler
    Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland
  • U. Schmidt-Erfurth
    Ophthalmology, Medical University of Vienna, Vienna, Austria
  • G. Gregori
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida
  • Footnotes
    Commercial Relationships  T.A. Abunto, Carl Zeiss Meditec, Inc., E; T. Callan, Carl Zeiss Meditec, Inc., E; P. Stetson, Carl Zeiss Meditec, Inc., E; M. Durbin, Carl Zeiss Meditec, Inc., E; M. Wieland, Carl Zeiss Meditec, Inc., C; N.M. Bressler, Carl Zeiss Meditec, Inc., F; U. Schmidt-Erfurth, Carl Zeiss Meditec, Inc., C; G. Gregori, Carl Zeiss Meditec, Inc., F.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 4244. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      T. A. Abunto, T. Callan, P. Stetson, M. Durbin, M. Wieland, N. M. Bressler, U. Schmidt-Erfurth, G. Gregori; Variability Between Trained Experts Performing Hand-Drawn Segmentations of CirrusTm HD-OCT Scans. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4244. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose:
 

To determine the differences between hand-drawn segmentations performed by three trained experts on images from CirrusTM HD-OCT, a spectral domain optical coherence tomography instrument (Carl Zeiss Meditec Inc., Dublin, CA).

 
Methods:
 

24 CirrusTM HD-OCT scans were randomly chosen from a database of 163 scans, classified by scan type and disease. Scans were done on consented subjects, following an IRB approved protocol. Hand-drawn segmentations on the internal limiting membrane (ILM) and retinal pigment epithelium (RPE) boundaries were performed by 3 trained experts on each scan. Differences between the three hand drawn segmentations were measured.

 
Results:
 

The mean absolute differences (MAD) averaged over all points in all scans are shown in Table 1. Specific cases were analyzed to understand factors causing these differences.Table 1. Mean absolute difference between hand drawn segmentations of three trained experts  

 
Conclusions:
 

In most disease categories, especially for the higher density 512x128 scans, there was good agreement between the three experts (MAD < 6 microns). Greater variability seen in specific groups appear to be influenced by various factors, such as individual interpretations of retinal anatomy, changes due to disease, scan type, image quality and amount of training. This variability should be taken into consideration as a contributing factor to differences seen when using hand drawn segmentations to validate the instrument’s automated segmentation algorithm.

 
Keywords: imaging/image analysis: clinical • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • retina 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×