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M. I. Seider, B. J. Lujan, P. J. Rosenfeld, G. Gregori, C. A. Puliafito; Posterior Pole Measurements Using Spectral Domain Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4273.
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© ARVO (1962-2015); The Authors (2016-present)
To measure the precise distance from the center of the optic disk to the foveola in patients without macular pathology using Spectral Domain Optical Coherence Tomography (SD-OCT).
SD-OCT optic nerve and macular cube scans were obtained from 53 right eyes. SD-OCT data sets were reviewed to confirm the absence of macular pathology and the presence of a distinct foveal depression. The location of the foveal center was identified by viewing horizontal and vertical cross-sectional images. The center of the optic disk was defined as halfway between the outer edge of the neuroretinal rim, horizontally and vertically, as seen on the reconstructed OCT fundus image. The calibrated macular and optic nerve reconstructed OCT fundus images were then combined to form an overlapping montage OCT fundus image using the retinal vessels. The horizontal and vertical displacements between the center of the optic disk and the foveal center were then measured, and the total linear distance and angle between the structures computed.
The mean angle between the optic nerve and the macula was -6.875 degrees with a standard deviation of 4.469 degrees, or 65% of the mean.
The total linear distance between the center of the fovea and the center of the optic nerve showed low variability, while there was a high degree of variability in the angle between the two structures. This suggests that the anatomical position of the optic disk and fovea relative to each other is highly invariate in this group of patients, but that there is a significant degree of rotation of the eye present when performing the SD-OCT scan. This information may be useful for developing a means to image patients with macular pathology that can not reliably fixate and have no identifiable foveal center.
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