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E. Spoerl, F. Raiskup-Wolf, E. Kuhlisch, L. E. Pillunat; Is There a Relation Between Cigarette Smoking and Keratoconus?. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4322.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate an association between cigarette smoking and keratoconus.
Keratoconus patients which were treated by corneal collagen crosslinking between June 2006 and November 2007 were asked anamnestically for their smoking habits. As smoker was included with at least daily 2 cigarettes for at least one year.
From June 2006 to November 2007 180 patients with keratoconus (age 28±9 years) were asked and 171 (95 %) were non-smoker and only 9 (5 %) were smoker. The frequency of smokers in the keratoconus group is 5 % with the 95 % confidential interval between 2,31% till 9,28 %. In the general population in the age range of 15 to 30 years the frequency of smokers is 30 - 40 %. With the Chi-square test there is a significant relation between non-smoker and keratoconus (P<0.001).
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