May 2008
Volume 49, Issue 13
ARVO Annual Meeting Abstract  |   May 2008
Clinical Changes of the Cornea in Keratoconus After UV-C3R X-Linking Treatment :A 12-18 Month Malaysian Study
Author Affiliations & Notes
  • J. P. Deva
    Ophthalmology, Ophir Eye Clinic/Tun Hussein Onn National Eye Hospital, KLANG/Kuala lumpur, Malaysia
  • Footnotes
    Commercial Relationships  J.P. Deva, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 4336. doi:
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    • Get Citation

      J. P. Deva; Clinical Changes of the Cornea in Keratoconus After UV-C3R X-Linking Treatment :A 12-18 Month Malaysian Study. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4336. doi:

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      © ARVO (1962-2015); The Authors (2016-present)

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To assess the Visual , Clinical and Stability Outcomes of theCornea 12-18months after UV-C3R X-Linking Treatment for Keratoconus_AMalaysian Study


Clinical cases of different ethnicity were selected consecutively.Allwere newly detected cases . Exclusion criteria included corneasbelow 300uSpecial debridement of the corneal epithelium wasdone, and then Riboflavin-Dextran solution was instilled for20mins. UV C3R Treatment was done for 30mins (Prof. T Sieleret al).Postoperative management was mainly with antibiotic andmild steroid drops to allow proper healing. of the epithelium..


Visual Acuity, Slitlamp examinations, Topography, Pachymetryand the Refractive Status as well as the RGP lens centrationwere studied at 1st, 3rd, 6month and thereafter 3monthly whereverpossible.Topographical changes were observed showing the apexof the cone becoming more centred accompanied by better centrationof the RGP contact lens.(Figs. below)


All cases experienced visual enhancement, and visual impairmentmeasurements by Logmar showed minimal visual impairment. TheRefractive Astigmatism was reduced in most cases by at least2dioptres. The cornea seems to stabilise in its refractive status.Therefore UV C3R Treatment may become a very promising proactivemethod of treating Keratoconus in early stages. in the nearfuture .  


Keywords: keratoconus • cornea: clinical science • contact lens 

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