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S. P. Azen, J. Chung, A. W. Foong, M. Torres, R. Varma, LALES Group; Four-Year Incidence of Visual Impairment in a Latino Population: The Los Angeles Latino Eye Study (LALES-II). Invest. Ophthalmol. Vis. Sci. 2008;49(13):4450.
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To present the 4-year incidence of visual impairment (VI) and blindness in a population based study of adult Latinos (primarily Mexican-Americans) age 40 and older who did not have VI at the baseline examination.
Participants underwent a detailed ophthalmologic examination including measurement of best-corrected distance visual acuity (BCVA) using a standard ETDRS protocol. 4-year binocular VI or blindness was defined as 1) baseline presenting visual acuity (PVA)>20/40 and a follow-up PVA<20/40, or 2) baseline PVA>20/200 and a follow-up PVA≤20/200. The US-modified criterion for 4-year monocular VI or blindness in either eye was defined as: 1) a baseline BCVA≥20/40 and a follow-up BCVA< 20/40 but ≥20/200, or 2) baseline BCVA>20/200 and a follow-up BCVA≤20/200. The WHO-modified criterion for 4-year monocular VI or blindness in either eye was defined as: 1) a baseline BCVA≥20/63 and a follow-up BCVA<20/63 but ≥20/400, or 2) baseline BCVA>20/400 and a follow-up BCVA<20/400.
Of the 4520 participants who underwent a follow-up eye examination, 4.6% had binocular visual impairment, 2.7%, 12.6% and 3.2% (US-modified) vs. 1.5%, 7.4% and 1.7% (WHO-modified) had monocular VI in the 1st eye, 2nd eye and 1st or 2nd eye, respectively. In addition, 1.2%, 8.8% and 1.3% (US-modified) vs. 0.9%, 10.2% and 1.0% (WHO-modified) had blindness in the 1st eye, 2nd eye and 1st or 2nd eye, respectively.
Age-specific incidence rates of VI and blindness in LALES-II are the highest reported in the U.S. Overall, the incidence of VI was considerably higher than that reported in the Beaver Dam Eye Study, which included primarily non-Hispanic white participants. Screening and intervention programs should primarily focus on the older Latino population.
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