May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Dynamic Measurement of Wavefront Aberration and Visual Acuity in the Human Eyes
Author Affiliations & Notes
  • Y. Wang
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China
  • J. Xu
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China
  • X. Sun
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China
  • R. Chu
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China
  • H. Zhuang
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China
  • J. He
    New England College of Optometry, Boston, Massachusetts
  • Footnotes
    Commercial Relationships  Y. Wang, None; J. Xu, None; X. Sun, None; R. Chu, None; H. Zhuang, None; J. He, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 4472. doi:https://doi.org/
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    • Get Citation

      Y. Wang, J. Xu, X. Sun, R. Chu, H. Zhuang, J. He; Dynamic Measurement of Wavefront Aberration and Visual Acuity in the Human Eyes. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4472. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To dynamically measure wavefront aberration and visual acuity in the dry eye and the normal eyes.

Methods: : Both right and left eyes of twenty one dry eye patients and fifteen normal subjects were tested for dynamic wavefront aberrations within 45 sec period using the Multi-file mode of a Hartmann-Shack wavefront sensor (WASCA) with a time resolution of one sec. Dynamic visual acuity (VA) was tested for the subjects within 150 sec using a multi-functional VA tester (MFVA-100) with a time resolution about two sec. Eye blink during the test period was also recorded.

Results: : Every subject showed dynamic change in both the RMS of wavefront aberrations and the visual acuity during the test period, but the change pattern varied substantially from individual to individual. The difference in amplitude of the change in wavefront aberration and VA (Maximum - Minimum) could be as great as 3 times between the subjects. While the dynamic change was blink-dependent for some subjects, relatively stable aberration or VA with eye blink was observed for others. Mean change was greater in the dry eye group than the normal group for either the higher order wavefront aberrations (t=4.12, p<0.00025) or the VA (t=2.92, p<0.005).

Conclusions: : We have successfully measured dynamic change in wavefront aberrations in the whole eye and the visual acuity with relatively high time resolution. Substantial variation in the patterns of dynamic changes between subjects was observed for both dry eye and normal groups, but the dye eye tends to vary more than normal eye.

Keywords: cornea: tears/tear film/dry eye • aberrations • visual acuity 
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