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C. Matsushima, M. Miura, T. Iwasaki; Three-Dimensional Optical Coherence Tomography Guided Vitrectomy for Proliferative Diabetic Retinopathy. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4530. doi: https://doi.org/.
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To evaluate the three-dimensional structures of proliferative membrane in proliferative diabetic retinopathy using three-dimensional optical coherence tomography (OCT). To detect the locations and the extents of the epicenters in proliferative membranes using three dimensional OCT data sets, and evaluate the usefulness for membrane resection in vitrectomy.
We prospectively examined 6 eyes of 6 patients with proliferative diabetic retinopathy. Three-dimensional OCT data sets were obtained using commercialized spectral-domain OCT (Topcon 3D -1000, center wavelength 840 nm, 18000 Ascan/sec). Using three-dimensional OCT data sets, the epicenters in proliferative membranes were detected. The extents and the locations of the epicenters were registered in the color fundus photograph images, and were compared with the findings during vitrectomy.
In all eyes, three-dimensional structures of proliferative membranes could be visualized, and the epicenters could be clearly detected. The extents and the locations of epicenters corresponded well with the findings during vitrectomy, and these information were useful for safe and secure surgical procedures in membrane resection.
Three-dimensional OCT is an effective tool to understand the three-dimensional structure of proliferative membrane in proliferative diabetic retinopathy. Detection of the epicenters is useful for planning the surgical procedure in vitrectomy, and for the education and the training of the vitrectomy,
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