May 2008
Volume 49, Issue 13
ARVO Annual Meeting Abstract  |   May 2008
Spatial Relationship Between Optic Disc Hemorrhages and Nerve Fiber Layer Defects
Author Affiliations & Notes
  • E. T. Vesti
    Eye Hospital, Helsinki Univ Central Hospital, Helsinki, Finland
  • M. Harju
    Eye Hospital, Helsinki Univ Central Hospital, Helsinki, Finland
  • Footnotes
    Commercial Relationships  E.T. Vesti, None; M. Harju, None.
  • Footnotes
    Support  the Glaucoma Foundation LUX, Finland and the Eye Foundation, Finland
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 4618. doi:
  • Views
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      E. T. Vesti, M. Harju; Spatial Relationship Between Optic Disc Hemorrhages and Nerve Fiber Layer Defects. Invest. Ophthalmol. Vis. Sci. 2008;49(13):4618.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

Purpose: : To study relationship between the location of the optic disc hemorrhages and retinal nerve fiber layer defects.

Methods: : 20 eyes of 20 patients (1 male, 19 females) with one or two optic disc hemorrhages were followed for 6 months. The median age was 65 years (range 50 - 81 years). 12 did not use any systemic medication. Of the 8 patients, 7 had high systemic blood pressure, 3 had asthma, and 3 had ischemic heart disease. A clinical ophthalmological examination (visual acuity, refraction, applanation tonometry, funduscopy after pupillary dilatation) and photography of the optic nerve head and retinal nerve fiber layer (RNFL) with a digital fundus camera were performed at the time of detection of the hemorrhage and 6 months thereafter. The location of the hemorrhages and RNFL defects were recorded as well as possible enlargement of the RNFL defects at 6 months.

Results: : Of the 20 eyes, 14 had glaucoma (4 primary open-angle glaucoma, 6 normal tension glaucoma, 3 pseudoexfoliative glaucoma, 1 pigmentary glaucoma) and 6 were healthy. 18 eyes had one hemorrhage and 2 eyes had two hemorrhages. Of the 22 hemorrhages, 13 were located inferiorly or infero-temporally, and 6 superiorly or supero-temporally. Two hemorrhages were located infero-nasally and one nasally. 12 of the 22 hemorrhages were located on the edge of a wedge-shaped RNFL defect, 6 in the area of a diffuse RNFL thinning, and in 4 eyes no RNFL loss was detected. In 9 eyes, also other RNFL defects than those in the proximity of the hemorrhage were detected. At the 6 month follow-up visit, 17 of the 22 hemorrhages had disappeared and no new hemorrhages had appeared. The size of the RNFL defects had remained stable.

Conclusions: : The optic disc hemorrhages seem to appear at the border of an existing RNFL defect or in the area of an existing diffuse RNFL loss. The extent of the RNFL loss doesn’t seem to change during 6 months follow-up.

Keywords: optic disc • nerve fiber layer • imaging/image analysis: clinical 

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.